The aminoglycoside antibiotic gentamicin (GM) is still widely used against infections by
Gram‐positive and Gram‐negative aerobic bacteria. Its therapeutic efficacy, however, is …

Reactive oxygen species (ROS) are essential mediators of normal cell physiology. However,
in the last few decades, it has become evident that ROS overproduction and/or alterations of …

BACKGROUND: Common complications of pregnancy arise in part from dysfunctional
placental development, and include gestational diabetes mellitus (GDM), intrauterine growth …

Oxidative stress has been linked to the pathogenesis of the major complications of diabetes
in the kidney, the heart, the eye or the vasculature. NADPH oxidases of the Nox family are a …

Fructose intake is linked with the increasing prevalence of insulin resistance, and insulin
resistance links Alzheimer's disease with impaired insulin signaling, oxidative damage …

Aldosterone itself has been reported to participate in mediating renal injury, and it was
confirmed that the aldosterone synthase CYP11B2 gene, protein, and aldosterone …

Fetal glucocorticoid excess leads to subsequent adult hypertension, but the mechanisms
involved in this developmental programming remain largely unknown. In this study we tested …

Peroxisome proliferator–activated receptors (PPAR) play a critical physiological role in
energy homeostasis, in inflammation, and a protective role in cardiovascular function. We …

The ever-growing global burden of congestive heart failure (CHF) and type 2 diabetes
mellitus (T2DM) as well as their co-existence necessitate that anti-diabetic pharmacotherapy …

[Frontiers in Bioscience S4, 651-670, January 1, 2012] 651 Nox enzymes and oxidative stress in
atherosclerosis Adrian Manea1,2, Page 1 [Frontiers in Bioscience S4, 651-670, January 1, 2012] …