[HTML][HTML] Natural products and synthetic analogs as a source of antitumor drugs

J Sharifi-Rad, A Ozleyen, T Boyunegmez Tumer… - Biomolecules, 2019 - mdpi.com
Cancer is a heterogeneous disease and one of the major issues of health concern,
especially for the public health system globally. Nature is a source of anticancer drugs with …

[HTML][HTML] Delivery of cancer therapies by synthetic and bio-inspired nanovectors

T Briolay, T Petithomme, M Fouet, N Nguyen-Pham… - Molecular cancer, 2021 - Springer
Background As a complement to the clinical development of new anticancer molecules,
innovations in therapeutic vectorization aim at solving issues related to tumor specificity and …

Antioxidant and antimicrobial capacity of Lactifluus rugatus and its antiproliferative activity on A549 cells

M Sevindik - Indian Journal of Traditional Knowledge (IJTK), 2020 - op.niscpr.res.in
In the present study, the antioxidant, antimicrobial potential and antiproliferative activity of
Lactifluus rugatus mushroom were determined. Thus, extracts of the mushroom were …

Navigating the synthesis of quinoline hybrid molecules as promising anticancer agents

P Panda, S Chakroborty - ChemistrySelect, 2020 - Wiley Online Library
The emergence of drug resistance and low specificity with side effects are the significant
challenges in pharmaceutical sectors for control of cancer nowadays. Notwithstanding, this …

[HTML][HTML] Anticancer activities of mushrooms: a neglected source for drug discovery

SK Panda, G Sahoo, SS Swain, W Luyten - Pharmaceuticals, 2022 - mdpi.com
Approximately 270 species of mushrooms have been reported as potentially useful for
human health. However, few mushrooms have been studied for bioactive compounds that …

[HTML][HTML] Anticancer Drug Discovery based on Natural products: from computational approaches to Clinical studies

P Chunarkar-Patil, M Kaleem, R Mishra, S Ray… - Biomedicines, 2024 - mdpi.com
Globally, malignancies cause one out of six mortalities, which is a serious health problem.
Cancer therapy has always been challenging, apart from major advances in …

[HTML][HTML] Synthetic and naturally occurring heterocyclic anticancer compounds with multiple biological targets

RK Amewu, PO Sakyi, D Osei-Safo, I Addae-Mensah - Molecules, 2021 - mdpi.com
Cancer is a complex group of diseases initiated by abnormal cell division with the potential
of spreading to other parts of the body. The advancement in the discoveries of omics and bio …

A recent development of new therapeutic agents and novel drug targets for cancer treatment

ZD Kifle, M Tadele, E Alemu, T Gedamu… - SAGE open …, 2021 - journals.sagepub.com
Despite recent advances in cancer diagnosis, prevention, detection, as well as
management, the disease is expected to be the top cause of death globally. The …

Magnetic nanochain-based smart drug delivery system with remote tunable drug release by a magnetic field

B Kang, MK Shin, S Han, I Oh, E Kim, J Park, HY Son… - BioChip Journal, 2022 - Springer
Considerable attention is given to drug delivery technology that efficiently delivers
appropriate levels of drug molecules to diseased sites with significant therapeutic efficacy …

Synthesis, anticancer evaluation, CDK2 inhibition, and apoptotic activity assessment with molecular docking modeling of new class of pyrazolo[1,5-a]pyrimidines

NH Metwally, MS Mohamed, EA Deeb - Research on Chemical …, 2021 - Springer
Cyanopyrazolo [1, 5-a] pyrimidine derivative 3 reacted with some aromatic aldehydes,
arenediazonium salts, hydrazine hydrate, and guanidine hydrochloride to create a series of …