Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis

L Radoshevich, P Cossart - Nature Reviews Microbiology, 2018 - nature.com
Listeria monocytogenes is a food-borne pathogen responsible for a disease called
listeriosis, which is potentially lethal in immunocompromised individuals. This bacterium, first …

Zooming in on common immune evasion mechanisms of pathogens in phagolysosomes: potential broad-spectrum therapeutic targets against infectious diseases

A Selvapandiyan, N Puri, P Kumar… - FEMS Microbiology …, 2023 - academic.oup.com
The intracellular viral, bacterial, or parasitic pathogens evade the host immune challenges to
propagate and cause fatal diseases. The microbes overpower host immunity at various …

Listeria monocytogenes: cell biology of invasion and intracellular growth

J Pizarro-Cerda, P Cossart - Microbiology spectrum, 2018 - Am Soc Microbiol
ABSTRACT The Gram-positive pathogen Listeria monocytogenes is able to promote its entry
into a diverse range of mammalian host cells by triggering plasma membrane remodeling …

Listeria monocytogenes exploits host exocytosis to promote cell-to-cell spread

GC Dowd, R Mortuza, M Bhalla… - Proceedings of the …, 2020 - National Acad Sciences
The facultative intracellular pathogen Listeria monocytogenes uses an actin-based motility
process to spread within human tissues. Filamentous actin from the human cell forms a tail …

The Diaphanous-Related Formins Promote Protrusion Formation and Cell-to-Cell Spread of Listeria monocytogenes

R Fattouh, H Kwon, MA Czuczman… - The Journal of …, 2015 - academic.oup.com
Abstract The Gram-positive bacterium Listeria monocytogenes is a facultative intracellular
pathogen whose virulence depends on its ability to spread from cell to cell within an infected …

The host GTPase Dynamin 2 modulates apical junction structure to control cell-to-cell spread of Listeria monocytogenes

S Tijoriwalla, T Liyanage, TUB Herath, N Lee… - Infection and …, 2024 - journals.asm.org
The food-borne pathogen Listeria monocytogenes uses actin-based motility to generate
plasma membrane protrusions that mediate the spread of bacteria between host cells. In …

Bacterial spread from cell to cell: beyond actin-based motility

CJ Kuehl, AM Dragoi, A Talman, H Agaisse - Trends in microbiology, 2015 - cell.com
Several intracellular pathogens display the ability to propagate within host tissues by
displaying actin-based motility in the cytosol of infected cells. As motile bacteria reach cell …

Shigella flexneri subverts host polarized exocytosis to enhance cell‐to‐cell spread

TUB Herath, A Roy, A Gianfelice… - Molecular …, 2021 - Wiley Online Library
Shigella flexneri is a gram‐negative bacterial pathogen that causes dysentery. Critical for
disease is the ability of Shigella to use an actin‐based motility (ABM) process to spread …

[HTML][HTML] Recent advances in understanding Listeria monocytogenes infection: the importance of subcellular and physiological context

DJV David, P Cossart - F1000Research, 2017 - ncbi.nlm.nih.gov
The bacterial pathogen Listeria monocytogenes (Lm) is the causative agent of listeriosis, a
rare but fatal foodborne disease. During infection, Lm can traverse several host barriers and …

Role of host GTPases in infection by Listeria monocytogenes

K Ireton, LA Rigano, GC Dowd - Cellular microbiology, 2014 - Wiley Online Library
The bacterial pathogen L isteria monocytogenes induces internalization into mammalian
cells and uses actin‐based motility to spread within tissues. L isteria accomplishes this …