A review on anticancer potential of bioactive heterocycle quinoline
The advent of Camptothecin added a new dimension in the field anticancer drug
development containing quinoline motif. Quinoline scaffold plays an important role in …
development containing quinoline motif. Quinoline scaffold plays an important role in …
Quinoline as a privileged scaffold in cancer drug discovery
VR Solomon, H Lee - Current medicinal chemistry, 2011 - ingentaconnect.com
Quinoline (1-azanaphthalene) is a heterocyclic aromatic nitrogen compound characterized
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …
by a double-ring structure that contains a benzene ring fused to pyridine at two adjacent …
Biocide effects of volatile organic compounds produced by potential biocontrol rhizobacteria on Sclerotinia sclerotiorum
A Giorgio, A De Stradis, P Lo Cantore… - Frontiers in …, 2015 - frontiersin.org
Six rhizobacteria isolated from common bean and able to protect bean plants from the
common bacterial blight (CBB) causal agent, were in vitro evaluated for their potential …
common bacterial blight (CBB) causal agent, were in vitro evaluated for their potential …
Synthesis, characterization and anti-cancer activity of hydrazide derivatives incorporating a quinoline moiety
Identification of the novel (E)-N′-((2-chloro-7-methoxyquinolin-3-yl) methylene)-3-
(phenylthio) propanehydrazide scaffold 18 has led to the development of a new series of …
(phenylthio) propanehydrazide scaffold 18 has led to the development of a new series of …
Ambident reactivity of phenolate anions revisited: a quantitative approach to phenolate reactivities
RJ Mayer, M Breugst, N Hampel… - The Journal of Organic …, 2019 - ACS Publications
Prompted by the observation that the regioselectivities of phenolate reactions (C versus O
attack) are opposite to the predictions by the principle of hard and soft acids and bases, we …
attack) are opposite to the predictions by the principle of hard and soft acids and bases, we …
Recent advances in the synthesis and biological activity of 8-hydroxyquinolines
Compounds containing the 8-hydroxyquinoline (8-HQ) 1 nucleus exhibit a wide range of
biological activities, including antimicrobial, anticancer, and antifungal effects. The chemistry …
biological activities, including antimicrobial, anticancer, and antifungal effects. The chemistry …
DNA targeting half sandwich Ru (II)-p-cymene-N^ N complexes as cancer cell imaging and terminating agents: Influence of regioisomers in cytotoxicity
For diagnosing and annihilating cancer in the human body, herein, we have adopted a one
pot convenient synthetic protocol to synthesize a library of half sandwich Ru (II)-p-cymene …
pot convenient synthetic protocol to synthesize a library of half sandwich Ru (II)-p-cymene …
One-step catalytic synthesis of alkyl-substituted quinolines
CE Meyet, CH Larsen - The Journal of Organic Chemistry, 2014 - ACS Publications
Difficult-to-access alkyl-substituted quinolines are formed directly from commercially
available anilines, aldehydes, and alkynes bearing a variety of substituents. Copper (II) …
available anilines, aldehydes, and alkynes bearing a variety of substituents. Copper (II) …
Synthesis and antiviral activity of substituted quercetins
Influenza viruses are important pathogens that cause respiratory infections in humans and
animals. In addition to vaccination, antiviral drugs against influenza virus play a significant …
animals. In addition to vaccination, antiviral drugs against influenza virus play a significant …
Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives
H Shiraki, MP Kozar, V Melendez… - Journal of medicinal …, 2011 - ACS Publications
In an attempt to separate the antimalarial activity of tafenoquine (3) from its hemolytic side
effects in glucose-6-phosphate dehydrogenase (G6PD) deficiency patients, a series of 5-aryl …
effects in glucose-6-phosphate dehydrogenase (G6PD) deficiency patients, a series of 5-aryl …