Red blood cells: Supercarriers for drugs, biologicals, and nanoparticles and inspiration for advanced delivery systems
CH Villa, AC Anselmo, S Mitragotri… - Advanced drug delivery …, 2016 - Elsevier
Red blood cells (RBCs) constitute a unique drug delivery system as a biologic or hybrid
carrier capable of greatly enhancing pharmacokinetics, altering pharmacodynamics (for …
carrier capable of greatly enhancing pharmacokinetics, altering pharmacodynamics (for …
Role of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism, and homeostasis
AJ Cura, A Carruthers - Comprehensive Physiology, 2011 - Wiley Online Library
The facilitated diffusion of glucose, galactose, fructose, urate, myoinositol, and
dehydroascorbic acid in mammals is catalyzed by a family of 14 monosaccharide transport …
dehydroascorbic acid in mammals is catalyzed by a family of 14 monosaccharide transport …
Microneedle patches loaded with nanovesicles for glucose transporter-mediated insulin delivery
Glucose-responsive insulin delivery systems that mimic insulin secretion activity in the
pancreas show great potential to improve clinical therapeutic outcomes for people with type …
pancreas show great potential to improve clinical therapeutic outcomes for people with type …
[HTML][HTML] Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification
The metabolic state of quiescent hematopoietic stem cells (HSCs) is an important regulator
of self-renewal, but it is unclear whether or how metabolic parameters contribute to HSC …
of self-renewal, but it is unclear whether or how metabolic parameters contribute to HSC …
Red blood cells for glucose‐responsive insulin delivery
Glucose‐responsive delivery of insulin mimicking the function of pancreatic β‐cells to
achieve meticulous control of blood glucose (BG) would revolutionize diabetes care. Here …
achieve meticulous control of blood glucose (BG) would revolutionize diabetes care. Here …
[HTML][HTML] Myths, artifacts, and fatal flaws: identifying limitations and opportunities in vitamin C research
AJ Michels, B Frei - Nutrients, 2013 - mdpi.com
Research progress to understand the role of vitamin C (ascorbic acid) in human health has
been slow in coming. This is predominantly the result of several flawed approaches to study …
been slow in coming. This is predominantly the result of several flawed approaches to study …
[HTML][HTML] Low red blood cell vitamin C concentrations induce red blood cell fragility: a link to diabetes via glucose, glucose transporters, and dehydroascorbic acid
Strategies to prevent diabetic microvascular angiopathy focus on the vascular endothelium.
Because red blood cells (RBCs) are less deformable in diabetes, we explored an original …
Because red blood cells (RBCs) are less deformable in diabetes, we explored an original …
Anemia and transfusion in the neonate
R Colombatti, L Sainati, D Trevisanuto - Seminars in Fetal and Neonatal …, 2016 - Elsevier
Neonatal anemia is a frequent occurrence in neonatal intensive care units. Red blood cell
transfusion criteria in case of blood loss are clearly defined but optimal hemoglobin or …
transfusion criteria in case of blood loss are clearly defined but optimal hemoglobin or …
Metabolic regulation of hematopoietic stem cell commitment and erythroid differentiation
L Oburoglu, M Romano, N Taylor… - Current Opinion in …, 2016 - journals.lww.com
Metabolic regulation of hematopoietic stem cell commitment a... : Current Opinion in
Hematology Metabolic regulation of hematopoietic stem cell commitment and erythroid …
Hematology Metabolic regulation of hematopoietic stem cell commitment and erythroid …
[HTML][HTML] An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism
P Gonzalez-Menendez, M Romano, H Yan… - Cell reports, 2021 - cell.com
The metabolic changes controlling the stepwise differentiation of hematopoietic stem and
progenitor cells (HSPCs) to mature erythrocytes are poorly understood. Here, we show that …
progenitor cells (HSPCs) to mature erythrocytes are poorly understood. Here, we show that …