[HTML][HTML] Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease

A Chait, LJ Den Hartigh - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Exercise effects on white adipose tissue: beiging and metabolic adaptations

KI Stanford, RJW Middelbeek, LJ Goodyear - Diabetes, 2015 - Am Diabetes Assoc
Regular physical activity and exercise training have long been known to cause adaptations
to white adipose tissue (WAT), including decreases in cell size and lipid content and …

Guidelines for animal exercise and training protocols for cardiovascular studies

DC Poole, SW Copp, TD Colburn… - American Journal …, 2020 - journals.physiology.org
Whole body exercise tolerance is the consummate example of integrative physiological
function among the metabolic, neuromuscular, cardiovascular, and respiratory systems …

Leptin is a growth factor for colonic epithelial cells

JCH Hardwick, GR Van Den Brink, GJ Offerhaus… - Gastroenterology, 2001 - Elsevier
Background & Aims: Obesity increases the risk of colon cancer, whereas physical activity
reduces the risk. Plasma levels of leptin increase in proportion to the level of obesity and are …

Exercise-induced adaptations to white and brown adipose tissue

AC Lehnig, KI Stanford - Journal of Experimental Biology, 2018 - journals.biologists.com
The beneficial effects of exercise on skeletal muscle and the cardiovascular system have
long been known. Recent studies have focused on investigating the effects of exercise on …

[HTML][HTML] Effects of exercise on brown and beige adipocytes

RS Dewal, KI Stanford - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2019 - Elsevier
Physical exercise leads to beneficial effects in numerous tissues and organ systems and
offers protection against obesity and type 2 diabetes. Recent studies have investigated the …

Hyperactivity in patients with anorexia nervosa and in semistarved rats: evidence for a pivotal role of hypoleptinemia

J Hebebrand, C Exner, K Hebebrand, C Holtkamp… - Physiology & …, 2003 - Elsevier
Patients with anorexia nervosa (AN) often show normal to elevated physical activity levels
despite severe weight loss and emaciation. This is seemingly in contrast to the loss of …

Leptin suppresses semi-starvation induced hyperactivity in rats: implications for anorexia nervosa

C Exner, J Hebebrand, H Remschmidt… - Molecular …, 2000 - nature.com
Semi-starvation induced hyperactivity (SIH) occurs in rodents upon caloric restriction. We
hypothesized that SIH is triggered by the decline in leptin secretion associated with food …

Muscle-adipose tissue cross talk

KI Stanford, LJ Goodyear - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Exercise training results in adaptations to both skeletal muscle and white adipose tissue
(WAT) and protects against metabolic disorders including obesity and type 2 diabetes …

Low dopamine D2 receptor increases vulnerability to obesity via reduced physical activity, not increased appetitive motivation

JA Beeler, RP Faust, S Turkson, H Ye, X Zhuang - Biological psychiatry, 2016 - Elsevier
Background The dopamine D 2 receptor (D 2 R) has received much attention in obesity
studies. Data indicate that D 2 R is reduced in obesity and that the TaqA1 D 2 R variant may …