Tumor-associated macrophages may either promote or suppress tumor growth depending
on their activation status. Interferon-γ (IFN-γ) has been identified as a key factor for inducing …

Psoriasis is a chronic inflammatory skin disease characterized by a relapsing-remitting
disease course and correlated with increased expression of proinflammatory cytokines, such …

Biological rhythms in birds are driven by the master clock, which includes the
suprachiasmatic nucleus, the pineal gland and the retina. Light/dark cycles are the cues that …

Objective Obesity-associated chronic inflammation, aka meta-inflammation, is a key
pathogenic driver for obesity-associated comorbidity. Growth hormone secretagogue …

The stimulator of IFN genes (STING) protein senses cyclic dinucleotides released in
response to double-stranded DNA and functions as an adaptor molecule for type I IFN (IFNI) …

Synthetic biology is a promising multidisciplinary field that brings together experts in
scientific disciplines from cell biology to engineering with the goal of constructing elements …

Inflammation plays an important role in host defense against external stimuli such as
infection by pathogen, endotoxin or chemical exposure by the production of the inflammatory …

Gastric cancer is one of the most prevalent cancer types worldwide, and its resistance to
cancer therapies, such as chemotherapy and radiotherapy, has made treating it a major …

Mesenchymal stromal cells (MSCs) are multipotent cells with abilities to exert
immunosuppressive response promoting tissue repair. Studies have shown that MSCs can …

CD163 is the macrophage receptor for uptake of hemoglobin-haptoglobin complexes. The
human receptor can be shed from the macrophage surface owing to a cleavage site for the …