Update on metal N-heterocyclic carbene complexes as potential anti-tumor metallodrugs

W Liu, R Gust - Coordination Chemistry Reviews, 2016 - Elsevier
The clinical success of platinum-based chemotherapeutic agents was of enormous impact
on the discovery of novel metal N-heterocyclic carbene (NHC) complexes as potential anti …

[HTML][HTML] Recent developments in the medicinal applications of silver-NHC complexes and imidazolium salts

NA Johnson, MR Southerland, WJ Youngs - Molecules, 2017 - mdpi.com
Because of their great structural diversity and multitude of chemical properties, N-
heterocyclic carbenes (NHCs) have been utilized in a variety of capacities. Most recently …

Recent advances in medicinal applications of coinage-metal (Cu and Ag) N-heterocyclic carbene complexes

M Marinelli, C Santini, M Pellei - Current Topics in Medicinal …, 2016 - ingentaconnect.com
The fascinating chemical properties of N-heterocyclic carbene (NHC) complexes showed
them to be a suitable class of complexes to be investigated for their applications as drugs in …

Increased aqueous solubility and proapoptotic activity of potassium koetjapate against human colorectal cancer cells

SF Jafari, MB Khadeer Ahamed… - Journal of Pharmacy …, 2014 - academic.oup.com
Objectives Recently, we have isolated koetjapic acid (KA) from S andoricum koetjape and
identified its selective anticancer potentiality against colorectal carcinoma. KA is quite likely …

Cytotoxic activity and apoptosis induction by a series Ag (I)-NHC complexes on human breast cancer cells and non-tumorigenic epithelial cell line

T Kutlu, I Yıldırım, H Karabıyık, A Kılınçlı… - Journal of Molecular …, 2021 - Elsevier
The main problems encountered in treatment with anticancer drugs, undesired side effects,
and toxicity. One of the most important parameters in cell transport is the lipophilic and …

Para-xylyl linked bis-imidazolium ionic liquids: A study of the conformers of the cation and of the anion-cation hydrogen bonding

B Haddad, A Paolone, M Drai, M Boumediene… - Journal of Molecular …, 2019 - Elsevier
In this work, two new para-xylyl linked bis-imidazolium Ionic Liquids (DILs), namely [pC 6 H
4 (CH 2 ImMe) 2][Cl−] 2 and [pC 6 H 4 (CH 2 ImMe) 2+][BF 4−] 2, are prepared from …

[HTML][HTML] Synthesis, crystal structures and spectroscopic properties of two new organotin (IV) complexes and their antiproliferative effect against cancerous and non …

YF Win, CS Choong, JC Dang, MA Iqbal… - Comptes Rendus …, 2015 - Elsevier
Cancer has become a leading cause of death worldwide, which is responsible for 7.6 million
cancer deaths according to GLOBOCAN survey conducted in 2008. The exploration of cis …

Colorectal, prostate and pancreas human cancers targeted bioassay-guided isolations and characterization of chemical constituents from Tephrosia apollinea

EA Hassan, M Adnan Iqbal, SS Dahham… - Anti-Cancer Agents …, 2017 - ingentaconnect.com
Background: Cancer is characterized by uncontrolled cell division caused by dysregulation
of cell proliferation. Therefore, agents that impair cancer cell proliferation could have …

Cytotoxic and Pro-Apoptotic Properties of Ethyl-p-Methoxycinnamate and Its Hydrophilic Derivative Potassium-p-Methoxycinnamate

MI Umar, MA Iqbal, MB Khadeer Ahamed, R Altaf… - Chemistry Africa, 2018 - Springer
Purpose The present study was designed to investigate the underlying mechanism of
cytotoxic and pro-apoptotic potential of ethyl-p-methoxycinnamate (EPMC) and its …

Synthesis, radiolabeling, and bioevaluation of Bis (trifluoromethanesulfonyl) imide

OA Ersöz, HM Soylu, O Er, K Ocakoglu… - Cancer Biotherapy …, 2015 - liebertpub.com
Imidazolium salts have antitumor potential and toxicological effects on various
microorganisms. The authors' aim is to synthesize a new imidazolium salt and to assess its …