Ring opening polymerization of α-amino acids: advances in synthesis, architecture and applications of polypeptides and their hybrids

AR Mazo, S Allison-Logan, F Karimi… - Chemical society …, 2020 - pubs.rsc.org
Polypeptides have attracted considerable attention in recent decades due to their inherent
biodegradability and tunable cytocompatibility. Macromolecular design in conjunction with …

Reactive‐oxygen‐species‐responsive drug delivery systems: promises and challenges

G Saravanakumar, J Kim, WJ Kim - Advanced Science, 2017 - Wiley Online Library
Given the increasing evidence indicates that many pathological conditions are associated
with elevated reactive oxygen species (ROS) levels, there have been growing research …

Thioether-based ROS responsive polymers for biomedical applications

M Criado-Gonzalez, D Mecerreyes - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Reactive oxygen species (ROS) play a key role in several biological functions of living
organisms such as regulation of cell signalling, production of some hormones, modulation of …

Synthesis of side-chain modified polypeptides

TJ Deming - Chemical reviews, 2016 - ACS Publications
Proteins have long fascinated scientists since their complex sequences and diversity of
chemical functionality can lead to structurally defined folded chains with highly specific …

Reactive oxygen species (ROS) responsive polymers for biomedical applications

Q Xu, C He, C Xiao, X Chen - Macromolecular bioscience, 2016 - Wiley Online Library
Reactive oxygen species (ROS) play important roles in cell signaling pathways, while
increased production of ROS may disrupt cellular homeostasis, giving rise to oxidative stress …

Biodegradable stimuli-responsive polypeptide materials prepared by ring opening polymerization

Y Shen, X Fu, W Fu, Z Li - Chemical Society Reviews, 2015 - pubs.rsc.org
The stimuli-responsive polypeptides have drawn extensive attention because of their
promising applications in biotechnology considering their biocompatibility, biodegradability …

Secondary structures of synthetic polypeptide polymers

C Bonduelle - Polymer Chemistry, 2018 - pubs.rsc.org
Synthetic peptide-based polymers represent a unique class of macromolecules able to
mimic the properties of natural proteins in materials sciences since (1) they present the …

Physical, chemical, and biological structures based on ROS‐sensitive moieties that are able to respond to oxidative microenvironments

C Tapeinos, A Pandit - Advanced Materials, 2016 - Wiley Online Library
Reactive oxygen species (ROS)(H2O2, OCl−,• OH, O2−) are a family of reactive molecules
that are generated intracellularly and are engaged in many biological processes. In …

Amino acid-derived stimuli-responsive polymers and their applications

K Bauri, M Nandi, P De - Polymer Chemistry, 2018 - pubs.rsc.org
Natural biopolymers such as proteins and nucleic acids in living organisms possess an
inherent ability to respond to local environmental stimuli, which motivated researchers to …

Redox-sensitive nanoscale drug delivery systems for cancer treatment

E Mirhadi, M Mashreghi, MF Maleki… - International journal of …, 2020 - Elsevier
Pharmaceutical nanotechnology introduces novel strategies in designing smart nanoscale
drug delivery systems (NDDSs) capable of responding to specific conditions. These smart …