A disinhibitory circuit for contextual modulation in primary visual cortex

AJ Keller, M Dipoppa, MM Roth, MS Caudill, A Ingrosso… - Neuron, 2020 - cell.com
Context guides perception by influencing stimulus saliency. Accordingly, in visual cortex,
responses to a stimulus are modulated by context, the visual scene surrounding the …

Origins of direction selectivity in the primate retina

YJ Kim, BB Peterson, JD Crook, HR Joo, J Wu… - Nature …, 2022 - nature.com
From mouse to primate, there is a striking discontinuity in our current understanding of the
neural coding of motion direction. In non-primate mammals, directionally selective cell types …

Retinal Connectomics: A Review

CL Sigulinsky, RL Pfeiffer… - Annual Review of Vision …, 2024 - annualreviews.org
The retina is an ideal model for understanding the fundamental rules for how neural
networks are constructed. The compact neural networks of the retina perform all of the initial …

Cortical synaptic architecture supports flexible sensory computations

B Scholl, D Fitzpatrick - Current opinion in neurobiology, 2020 - Elsevier
Highlights•Functional properties of excitatory inputs onto cortical neurons are more
diverse.•Cortical neurons can receive imbalanced synaptic excitation and inhibition.•Current …

Classical center-surround receptive fields facilitate novel object detection in retinal bipolar cells

JA Gaynes, SA Budoff, MJ Grybko, JB Hunt… - Nature …, 2022 - nature.com
Antagonistic interactions between center and surround receptive field (RF) components lie
at the heart of the computations performed in the visual system. Circularly symmetric center …

Cholinergic feedback to bipolar cells contributes to motion detection in the mouse retina

CB Hellmer, LM Hall, JM Bohl, ZJ Sharpe, RG Smith… - Cell reports, 2021 - cell.com
Retinal bipolar cells are second-order neurons that transmit basic features of the visual
scene to postsynaptic partners. However, their contribution to motion detection has not been …

Corticothalamic feedback sculpts visual spatial integration in mouse thalamus

G Born, FA Schneider-Soupiadis, S Erisken… - Nature …, 2021 - nature.com
En route from the retina to the cortex, visual information passes through the dorsolateral
geniculate nucleus (dLGN) of the thalamus, where extensive corticothalamic (CT) feedback …

Direction selectivity in retinal bipolar cell axon terminals

A Matsumoto, W Agbariah, SS Nolte, R Andrawos… - Neuron, 2021 - cell.com
The ability to encode the direction of image motion is fundamental to our sense of vision.
Direction selectivity along the four cardinal directions is thought to originate in direction …

Center-surround interactions underlie bipolar cell motion sensitivity in the mouse retina

S Strauss, MM Korympidou, Y Ran, K Franke… - Nature …, 2022 - nature.com
Motion sensing is a critical aspect of vision. We studied the representation of motion in
mouse retinal bipolar cells and found that some bipolar cells are radially direction selective …

Compartmentalized pooling generates orientation selectivity in wide-field amacrine cells

W Lei, DA Clark, JB Demb - Proceedings of the National Academy of …, 2024 - pnas.org
Orientation is one of the most salient features in visual scenes. Neurons at multiple levels of
the visual system detect orientation, but in many cases, the underlying biophysical …