Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment

RA McCutcheon, RSE Keefe, PK McGuire - Molecular psychiatry, 2023 - nature.com
Cognitive deficits are a core feature of schizophrenia, account for much of the impaired
functioning associated with the disorder and are not responsive to existing treatments. In this …

Effectiveness, core elements, and moderators of response of cognitive remediation for schizophrenia: a systematic review and meta-analysis of randomized clinical …

A Vita, S Barlati, A Ceraso, G Nibbio, C Ariu… - JAMA …, 2021 - jamanetwork.com
Importance Cognitive impairment is a core feature of schizophrenia, with negative
consequences on functional outcomes. Although cognitive remediation (CR) is effective and …

The clinical characterization of the patient with primary psychosis aimed at personalization of management

M Maj, J van Os, M De Hert, W Gaebel… - World …, 2021 - Wiley Online Library
The current management of patients with primary psychosis worldwide is often remarkably
stereotyped. In almost all cases an antipsychotic medication is prescribed, with second …

Cognitive impairment in people with schizophrenia: an umbrella review

Y Gebreegziabhere, K Habatmu, A Mihretu… - European archives of …, 2022 - Springer
Cognitive impairment is one of the core symptoms of schizophrenia. Quite a number of
systematic reviews were published related to cognitive impairment in people with …

Nonsocial and social cognition in schizophrenia: current evidence and future directions

MF Green, WP Horan, J Lee - World psychiatry, 2019 - Wiley Online Library
Cognitive impairment in schizophrenia involves a broad array of nonsocial and social
cognitive domains. It is a core feature of the illness, and one with substantial implications for …

Antipsychotics: mechanisms underlying clinical response and side-effects and novel treatment approaches based on pathophysiology

SJ Kaar, S Natesan, R Mccutcheon, OD Howes - Neuropharmacology, 2020 - Elsevier
Antipsychotic drugs are central to the treatment of schizophrenia and other psychotic
disorders but are ineffective for some patients and associated with side-effects and …

Aerobic exercise improves cognitive functioning in people with schizophrenia: a systematic review and meta-analysis

J Firth, B Stubbs, S Rosenbaum… - Schizophrenia …, 2017 - academic.oup.com
Cognitive deficits are pervasive among people with schizophrenia and treatment options are
limited. There has been an increased interest in the neurocognitive benefits of exercise, but …

Pathways to functional outcomes in schizophrenia spectrum disorders: Meta-analysis of social cognitive and neurocognitive predictors

TF Halverson, M Orleans-Pobee, C Merritt… - Neuroscience & …, 2019 - Elsevier
The current meta-analysis explored relationships between functional outcomes in
schizophrenia spectrum disorders and different domains of neurocognition and social …

[HTML][HTML] The effect of active video games on cognitive functioning in clinical and non-clinical populations: A meta-analysis of randomized controlled trials

E Stanmore, B Stubbs, D Vancampfort… - Neuroscience & …, 2017 - Elsevier
Physically-active video games ('exergames') have recently gained popularity for leisure and
entertainment purposes. Using exergames to combine physical activity and cognitively …

European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia

A Vita, W Gaebel, A Mucci, G Sachs, A Erfurth… - European …, 2022 - cambridge.org
Background Impairment in a wide range of cognitive abilities has been consistently reported
in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are …