DNA sequencing at 40: past, present and future
This review commemorates the 40th anniversary of DNA sequencing, a period in which we
have already witnessed multiple technological revolutions and a growth in scale from a few …
have already witnessed multiple technological revolutions and a growth in scale from a few …
[HTML][HTML] Long walk to genomics: History and current approaches to genome sequencing and assembly
Genomes represent the starting point of genetic studies. Since the discovery of DNA
structure, scientists have devoted great efforts to determine their sequence in an exact way …
structure, scientists have devoted great efforts to determine their sequence in an exact way …
Analysis of RNA-Seq data using TopHat and Cufflinks
S Ghosh, CKK Chan - Plant Bioinformatics: Methods and Protocols, 2016 - Springer
The recent advances in high throughput RNA sequencing (RNA-Seq) have generated huge
amounts of data in a very short span of time for a single sample. These data have required …
amounts of data in a very short span of time for a single sample. These data have required …
Cancer transcriptome profiling at the juncture of clinical translation
M Cieślik, AM Chinnaiyan - Nature Reviews Genetics, 2018 - nature.com
Methodological breakthroughs over the past four decades have repeatedly revolutionized
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …
Chemical ecology of endophytic fungi: origins of secondary metabolites
S Kusari, C Hertweck, M Spiteller - Chemistry & biology, 2012 - cell.com
Endophytes constitute a remarkably multifarious group of microorganisms ubiquitous in
plants and maintain an imperceptible association with their hosts for at least a part of their …
plants and maintain an imperceptible association with their hosts for at least a part of their …
High-throughput transcriptome profiling in drug and biomarker discovery
The development of new drugs is multidisciplinary and systematic work. High-throughput
techniques based on “-omics” have driven the discovery of biomarkers in diseases and …
techniques based on “-omics” have driven the discovery of biomarkers in diseases and …
Gene expression profiling of plants under salt stress
Soil salinity is among the leading environmental stresses affecting global agriculture,
causing billions of dollars in crop damages every year. Regardless of the cause, ion toxicity …
causing billions of dollars in crop damages every year. Regardless of the cause, ion toxicity …
Transcriptomics technologies
Transcriptomics technologies are the techniques used to study an organism's transcriptome,
the sum of all of its RNA transcripts. The information content of an organism is recorded in …
the sum of all of its RNA transcripts. The information content of an organism is recorded in …
RNA-Seq: a revolutionary tool for transcriptomics
RNA-Seq is a recently developed approach to transcriptome profiling that uses deep-
sequencing technologies. Studies using this method have already altered our view of the …
sequencing technologies. Studies using this method have already altered our view of the …