Kynurenines: Tryptophan's metabolites in exercise, inflammation, and mental health
BACKGROUND The essential amino acid tryptophan is a substrate for the generation of
several bioactive compounds with important physiological roles. Only a small fraction of …
several bioactive compounds with important physiological roles. Only a small fraction of …
Metabolomics in infectious diseases and drug discovery
Metabolomics has emerged as an invaluable tool that can be used along with genomics,
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …
CD4: CD8 ratio as a frontier marker for clinical outcome, immune dysfunction and viral reservoir size in virologically suppressed HIV‐positive patients
Methods A comprehensive review of the English‐language publications was implemented.
We searched PubMed, JSTOR and Scopus electronic databases with keyword combinations …
We searched PubMed, JSTOR and Scopus electronic databases with keyword combinations …
The Bacterium Akkermansia muciniphila: A Sentinel for Gut Permeability and Its Relevance to HIV-Related Inflammation
Gut dysbiosis, namely dysregulation of the intestinal microbiota, and increased gut
permeability lead to enhanced inflammation and are commonly seen in chronic conditions …
permeability lead to enhanced inflammation and are commonly seen in chronic conditions …
Exosome markers associated with immune activation and oxidative stress in HIV patients on antiretroviral therapy
S Chettimada, DR Lorenz, V Misra, ST Dillon… - Scientific reports, 2018 - nature.com
Exosomes are nanovesicles released from most cell types including immune cells. Prior
studies suggest exosomes play a role in HIV pathogenesis, but little is known about …
studies suggest exosomes play a role in HIV pathogenesis, but little is known about …
Oncogenic effects of HIV-1 proteins, mechanisms behind
M Isaguliants, E Bayurova, D Avdoshina… - Cancers, 2021 - mdpi.com
Simple Summary People living with human immunodeficiency virus type 1 (HIV-1)(PLWH)
are at increased risk of developing cancer despite successful antiretroviral therapy (ART) …
are at increased risk of developing cancer despite successful antiretroviral therapy (ART) …
Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection
C Tincati, DC Douek, G Marchetti - AIDS research and therapy, 2016 - Springer
Over the past 10 years, extensive work has been carried out in the field of microbial
translocation in HIV infection, ranging from studies on its clinical significance to …
translocation in HIV infection, ranging from studies on its clinical significance to …
Clinical and public health implications of acute and early HIV detection and treatment: a scoping review
SE Rutstein, J Ananworanich, S Fidler… - African Journal of …, 2017 - journals.lww.com
Methods We conducted a scoping review [28] synthesizing the most recent literature on
clinical and public health implications of widespread AHI detection and treatment. This …
clinical and public health implications of widespread AHI detection and treatment. This …
Mechanisms of CD8+ T cell‐mediated suppression of HIV/SIV replication
JB McBrien, NA Kumar… - European journal of …, 2018 - Wiley Online Library
In this article, we summarize the role of CD8+ T cells during natural and antiretroviral
therapy (ART)‐treated HIV and SIV infections, discuss the mechanisms responsible for their …
therapy (ART)‐treated HIV and SIV infections, discuss the mechanisms responsible for their …
CD8+ T-Cell Response to HIV Infection in the Era of Antiretroviral Therapy
Although the combined antiretroviral therapy (cART) has decreased the deaths associated
with the immune deficiency acquired syndrome (AIDS), non-AIDS conditions have emerged …
with the immune deficiency acquired syndrome (AIDS), non-AIDS conditions have emerged …