Clustered regularly interspersed short pallindromic repeats (CRISPR) and CRISPR
associated proteins (Cas) system (CRISPR-Cas) came into light as prokaryotic defence …

Targeted genome editing technologies are becoming the most important and widely used
genetic tools in studies of phytopathology. The “clustered regularly interspaced short …

Rapid and accurate detection of biomarkers was very important for early screening and
treatment of diseases. Herein, a sensitive and amplification-free electrochemiluminescence …

A genome-based systematic analysis combined with phenotypic experiments was
conducted to evaluate the safety properties and metabolic characteristics of Streptococcus …

Bacteria have evolved a diverse set of enzymes that enable them to subvert host defense
mechanisms as well as to form part of the prokaryotic immune system. Due to their unique …

The use of biomaterials in delivering CRISPR/Cas9 for gene therapy in infectious diseases
holds tremendous potential. This innovative approach combines the advantages of …

Cancer is the second most common cause of death globally and is a major public health
concern. Managing this disease is difficult due to its multiple stages and numerous genetic …

The MHC-I antigen presentation (AP) pathway is key to shaping mammalian CD8+ T cell
immunity, with its aberrant expression closely linked to low tumor immunogenicity and …

Gene mutation correction was challenging until the discovery of clustered regularly
interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) …

Triple negative breast cancer (TNBC) has been well-known to be closely associated with the
abnormal expression of both oncogenes and tumor suppressors. Although several …