Evolving landscape of detection and targeting miRNA/epigenetics for therapeutic strategies in ovarian cancer

AD Bhowmik, P Shaw, MSG Pillai, G Rao, SKD Dwivedi - Cancer Letters, 2025 - Elsevier
Ovarian cancer (OC) accounts for the highest mortality rates among all gynecologic
malignancies. The high mortality of OC is often associated with delayed detection …

Paradigm Shift: A Comprehensive Review of Ovarian Cancer Management in an Era of Advancements

V Tavares, IS Marques, IG Melo, J Assis… - International Journal of …, 2024 - mdpi.com
Ovarian cancer (OC) is the female genital malignancy with the highest lethality. Patients
present a poor prognosis mainly due to the late clinical presentation allied with the common …

TGM2, HMGA2, FXYD3, and LGALS4 genes as biomarkers in acquired oxaliplatin resistance of human colorectal cancer: A systems biology approach

T Cheraghi-Shavi, R Jalal, Z Minuchehr - PLoS One, 2023 - journals.plos.org
Acquired resistance to oxaliplatin is considered as the primary reason for failure in colorectal
cancer (CRC) therapy. Identifying the underlying resistance mechanisms may improve CRC …

Differential molecular pathway expression according to chemotherapeutic response in ovarian clear cell carcinoma

M Yin, C Lu, H Zhou, Q Liu, J Yang - BMC Women's Health, 2023 - Springer
Objective Ovarian clear cell carcinoma (OCCC) is a distinct entity from epithelial ovarian
cancer. The prognosis of advanced and recurrent disease is very poor due to resistance to …

Enhancing precision medicine: a nomogram for predicting platinum resistance in epithelial ovarian cancer

R Li, Z Xiong, Y Ma, Y Li, Y Yang, S Ma… - World Journal of Surgical …, 2024 - Springer
Background This study aimed to develop a novel nomogram that can accurately estimate
platinum resistance to enhance precision medicine in epithelial ovarian cancer (EOC) …

[HTML][HTML] Novel Molecular Mechanisms Underlying the Ameliorative Effect of Platelet-Rich Plasma against Electron Radiation-Induced Premature Ovarian Failure

G Demyashkin, M Vadyukhin, Z Murtazalieva… - International Journal of …, 2024 - mdpi.com
Radiotherapy is one of the risk factors for radiation-induced premature ovarian failure and
infertility in cancer patients. The development of methods for ovarian radioprotection …

[HTML][HTML] Exploring miRNA profile associated with cisplatin resistance in ovarian cancer cells

Y Alghamian, C Soukkarieh, A Aljapawe… - … and Biophysics Reports, 2025 - Elsevier
Ovarian cancer is a common and lethal malignancy among women, whereas
chemoresistance is one of the major challenges to its treatment and prognosis …

Gene Expression Profiles in Ovarian Cancer Tissues as a Potential Tool to Predict Platinum-based Chemotherapy Resistance

M Talijanovic, J Lopacinska-Jørgensen… - Anticancer …, 2025 - ar.iiarjournals.org
Background/Aim: Ovarian cancer (OC) is one of the leading gynecological causes of death
among women. The current standard treatment for OC is debulking surgery followed by …

Anti-cancer effects of alpha lipoic acid, cisplatin and paclitaxel combination in the OVCAR-3 ovarian adenocarcinoma cell line

HŞ Çoban, N Çil, E Önder, G Abban Mete - Molecular Biology Reports, 2024 - Springer
Background Ovarian cancer is the leading cause of gynecological cancer deaths. One of the
major challenges in treating ovarian cancer with chemotherapy is managing the resistance …

Application value of Ki67 and serum CA125 in the deep myometrial invasion of endometrial adenocarcinoma

L Qin - BMC cancer, 2023 - Springer
Objective To investigate the application value of Ki67 and serum CA125 in diagnosing the
deep myometrial invasion of endometrial adenocarcinoma. Methods This study …