REGULATORY ROLES OF microRNAs IN MODULATING MITOCHONDRIAL DYNAMICS, AMYLOID BETA FIBRILLATION, MICROGLIAL ACTIVATION, AND …
M Sharma, AK Tanwar, PK Purohit, P Pal… - Neuroscience & …, 2024 - Elsevier
Alzheimer's Disease (AD) remains a formidable challenge due to its complex pathology,
notably involving mitochondrial dysfunction and dysregulated microRNA (miRNA) signaling …
notably involving mitochondrial dysfunction and dysregulated microRNA (miRNA) signaling …
Key genes and biochemical networks in various brain regions affected in Alzheimer's disease
M Abyadeh, N Tofigh, S Hosseinian, M Hasan… - Cells, 2022 - mdpi.com
Alzheimer's disease (AD) is one of the most complicated progressive neurodegenerative
brain disorders, affecting millions of people around the world. Ageing remains one of the …
brain disorders, affecting millions of people around the world. Ageing remains one of the …
Study of Early Onset Schizophrenia: Associations of GRIN2A and GRIN2B Polymorphisms
EG Poltavskaya, OY Fedorenko, EG Kornetova… - Life, 2021 - mdpi.com
Background: Schizophrenia is a complex mental disorder with a high heritability.
Dysfunction of the N-methyl-D-aspartate (NMDA)-type glutamate receptors may be involved …
Dysfunction of the N-methyl-D-aspartate (NMDA)-type glutamate receptors may be involved …
Posterior cingulate cortex reveals an expression profile of resilience in cognitively intact elders
CM Kelley, SD Ginsberg, WS Liang… - Brain …, 2022 - academic.oup.com
The posterior cingulate cortex, a key hub of the default mode network, underlies
autobiographical memory retrieval and displays hypometabolic changes early in Alzheimer …
autobiographical memory retrieval and displays hypometabolic changes early in Alzheimer …
Investigation of the multi-targeted protection potential of tannic acid against doxorubicin-induced kidney damage in rats
EN Yesilkent, H Ceylan - Chemico-biological interactions, 2022 - Elsevier
Doxorubicin (DOX) is an antitumor drug that is powerful but can cause worse outcomes,
including nephrotoxicity, and therefore has limited clinical use. Therefore, it is necessary to …
including nephrotoxicity, and therefore has limited clinical use. Therefore, it is necessary to …
Bioinformatics‐based identification of hepatocellular carcinoma‐associated hub genes and assessment of the restorative effect of tannic acid in rat liver exposed to …
H Tosun, H Karadas, H Ceylan - Cancer Medicine, 2024 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) is the most common type of primary liver
cancer, occurring mostly in individuals with chronic liver disease, but biomarkers for …
cancer, occurring mostly in individuals with chronic liver disease, but biomarkers for …
Hederagenin Upregulates PTPN1 Expression in Aβ-Stimulated Neuronal Cells, Exerting Anti-Oxidative Stress and Anti-Apoptotic Activities
K Li, Y Wang, H Ni - Journal of Molecular Neuroscience, 2023 - Springer
Alzheimer's disease (AD) is a prevalently neurodegenerative disease characterized by
neuronal damage which is associated with amyloid-β (Aβ) accumulation. Hederagenin is a …
neuronal damage which is associated with amyloid-β (Aβ) accumulation. Hederagenin is a …
Recent applications of bioinformatics in target identification and drug discovery for Alzheimer's disease
Alzheimer's disease (AD) is a complex multifactorial neurodegenerative disease
characterized by progressive memory loss. The main pathological features of the disease …
characterized by progressive memory loss. The main pathological features of the disease …
Neuroprotective potential of tannic acid against neurotoxic outputs of monosodium glutamate in rat cerebral cortex
MS Karagac, H Ceylan - Neurotoxicity Research, 2023 - Springer
Glutamate in monosodium glutamate (MSG), which is widely used in the food industry, has
an important role in major brain functions such as memory, learning, synapse formation, and …
an important role in major brain functions such as memory, learning, synapse formation, and …
Transcriptomic Analyses of Exercise Training in Alzheimer's Disease Cerebral Cortex
MA Widjaya, YJ Cheng, YM Kuo, CH Liu… - Journal of …, 2023 - content.iospress.com
Background: Research reported exercise could reduce Alzheimer's disease (AD) symptoms
in human and animals. However, the molecular mechanism of exercise training via …
in human and animals. However, the molecular mechanism of exercise training via …