Heparin-binding correlates with increased efficiency of AAV1-and AAV6-mediated transduction of striated muscle, but negatively impacts CNS transduction

ALH Arnett, LR Beutler, A Quintana, J Allen, E Finn… - Gene therapy, 2013 - nature.com
Gene delivery vectors derived from adeno-associated virus (AAV) have great potential as
therapeutic agents. rAAV1 and rAAV6, efficiently target striated muscle, but the mechanisms …

[图书][B] Properties and techniques of intravascular rAAV6 gene delivery to striated muscle

BR Schultz - 2009 - search.proquest.com
A growing body of research supports the development of recombinant adeno-associated
viral vectors (rAAV) for delivery of gene expression cassettes to striated musculature as a …