Sirtuins as Potential Targets for Neuroprotection: Mechanisms of Early Brain Injury Induced by Subarachnoid Hemorrhage

K Lei, R Wu, J Wang, X Lei, E Zhou, R Fan… - Translational Stroke …, 2023 - Springer
Subarachnoid hemorrhage (SAH) is a prevalent cerebrovascular disease with significant
global mortality and morbidity rates. Despite advancements in pharmacological and surgical …

Melatonin as a potential neuroprotectant: mechanisms in subarachnoid hemorrhage-induced early brain injury

C Xu, Z He, J Li - Frontiers in Aging Neuroscience, 2022 - frontiersin.org
Subarachnoid hemorrhage (SAH) is a common cerebrovascular disease with high mortality
and disability rates. Despite progressive advances in drugs and surgical techniques …

[HTML][HTML] The use of wearable pulse oximeters in the prompt detection of hypoxemia and during movement: Diagnostic accuracy study

M Santos, S Vollam, MAF Pimentel, C Areia… - Journal of Medical …, 2022 - jmir.org
Background Commercially available wearable (ambulatory) pulse oximeters have been
recommended as a method for managing patients at risk of physiological deterioration, such …

Protective effect of Neferine in permanent cerebral ischemic rats via anti-oxidative and anti-apoptotic mechanisms

J Sengking, C Oka, N Yawoot, J Tocharus… - Neurotoxicity …, 2022 - Springer
Permanent cerebral ischemia is a consequence of prolonged cerebral artery occlusion that
results in severe brain damage. Neurotoxicity occurring after ischemia can induce brain …

CT‐Based Classification of Acute Cerebral Edema: Association with Intracranial Pressure and Outcome

S Lietke, S Zausinger, M Patzig… - Journal of …, 2020 - Wiley Online Library
ABSTRACT BACKGROUND AND PURPOSE Brain edema after acute cerebral lesions may
lead to raised intracranial pressure (ICP) and worsen outcome. Notwithstanding, no CT …

The Oxford study of Calcium channel Antagonism, Cognition, Mood instability and Sleep (OxCaMS): study protocol for a randomised controlled, experimental …

LZ Atkinson, L Colbourne, A Smith, CH Harmer… - Trials, 2019 - Springer
Background The discovery that voltage-gated calcium channel genes such as CACNA1C
are part of the aetiology of psychiatric disorders has rekindled interest in the therapeutic …

Cerebrospinal fluid concentrations of nimodipine correlate with long-term outcome in aneurysmal subarachnoid hemorrhage: pilot study

R Riva, M Pegoli, M Contin, A Perrone… - Clinical …, 2019 - journals.lww.com
Objectives The aim was to evaluate plasma and cerebrospinal fluid (CSF) nimodipine
concentrations in patients with aneurysmal subarachnoid hemorrhage and their correlation …

Dissolving microneedles loaded with nimodipine for prevention of sleep disorders at a high altitude

C Wang, X Huang, Z Tang, Y Zhang, M Wei… - Pharmaceutical …, 2024 - Taylor & Francis
Sleep disorders are one of the most common acute reactions on the plateau, which can
cause serious complications. However, there is no effective and safe treatment currently …

Oxygen sensor of the heart

JC Fernández-Morales, M Morad - Canadian Journal of …, 2022 - cdnsciencepub.com
How oxygen is sensed by the heart and what mechanisms mediate its sensing remain
poorly understood. As recent reports show that low PO2 levels are detected by the …

Protocol for a prospective, controlled, cross-sectional, diagnostic accuracy study to evaluate the specificity and sensitivity of ambulatory monitoring systems in the …

C Areia, S Vollam, P Piper, E King, J Ede, L Young… - BMJ open, 2020 - bmjopen.bmj.com
Introduction Automated continuous ambulatory monitoring may provide an alternative to
intermittent manual vital signs monitoring. This has the potential to improve frequency of …