Joint replacement is a major orthopaedic procedure used to treat joint osteoarthritis. Aseptic
loosening and infection are the two most significant causes of prosthetic implant failure. The …

Chitin and chitosan based nanocomposite scaffolds have been widely used for bone tissue
engineering. These chitin and chitosan based scaffolds were reinforced with …

Titanium (Ti) osseointegration is critical for the success of dental and orthopedic implants.
Previous studies have shown that surface roughness at the micro-and submicro-scales …

There is currently an unmet need for the supply of autologous, patient-specific stem cells for
regenerative therapies in the clinic. Mesenchymal stem cell differentiation can be driven by …

Current trends in clinical dental implant therapy include use of endosseous dental implant
surfaces embellished with nanoscale topographies. The goal of this review is to consider the …

Control of inflammation is indispensable for optimal oral wound healing and tissue
regeneration. Several biomaterials have been used to enhance the regenerative outcomes; …

The nanoscale surface topography of artificial materials is known to play a significant role in
interactions with biological systems such as proteins and cells. A detailed understanding …

Human tissues are intricate ensembles of multiple cell types embedded in complex and well-
defined structures of the extracellular matrix (ECM). The organization of ECM is frequently …

Since the founding of the osseointegration concept, the characteristics of the interface
between bone and implant, and possible ways to improve it, have been of particular interest …

The dynamic nature of the skeleton is achieved by a process called “remodeling” which
involves the co-ordinated actions of osteoclasts, osteoblasts, osteocytes within the bone …