Peptides, short protein fragments, can emulate the functions of their full-length native
counterparts. Peptides are considered potent recombinant protein alternatives due to their …

Osteosarcoma as an aggressive malignant neoplasm is commonly treated by surgical
resection, chemotherapy, and radiotherapy, but surgery induces bone defects and …

Peptide-based supramolecular gels can be designed to be functional “smart” materials that
have applications in drug delivery, tissue engineering, and supramolecular chemistry …

Dentin phosphoprotein (DPP) is a major component of the dentin matrix playing crucial role
in hydroxyapatite deposition during bone mineralization, making it a prime candidate for the …

Traditional methods to assess hMSCs differentiation typically require long-term culture until
cells show marked expression of histological markers such as lipid accumulation inside the …

Mineral deposition is observed in both bacterial and eukaryotic organisms through a broad
range of mechanisms. Both organic and inorganic components play crucial roles in the …

Mesenchymal stem cells (MSCs) are multipotent stem cells that can support various tissues
including bone marrow, adipose tissue, and synovial fluids, from which they can be readily …

Biological feedback mechanisms exert precise control over the initiation and termination of
molecular self-assembly in response to environmental stimuli, while minimizing the …

Organ or tissue loss due to accidents, diseases, or aging has been a major problem in
medicine which until recently could have only been alleviated with organ or tissue …

Supramolecular peptide nanofibers that are composed of peptide amphiphile molecules
have been widely used for many purposes from biomedical applications to energy …