One year in review 2020: comorbidities, diagnosis and treatment of primary Sjogren's syndrome

V Manfrè, G Cafaro, I Riccucci, A Zabotti… - Clinical and …, 2021 - research.rug.nl
Primary Sjogren's syndrome (pSS) is a complex and heterogeneous disorder characterised
by a wide spectrum of glandular and extra-glandular features. The discovery of novel …

Corneal regeneration using adipose-derived mesenchymal stem cells

JL Alió del Barrio, A De la Mata, MP De Miguel… - Cells, 2022 - mdpi.com
Adipose-derived stem cells are a subtype of mesenchymal stem cell that offers the important
advantage of being easily obtained (in an autologous manner) from low invasive …

Labial gland-derived mesenchymal stem cells and their exosomes ameliorate murine Sjögren's syndrome by modulating the balance of Treg and Th17 cells

B Li, Y Xing, Y Gan, J He, H Hua - Stem Cell Research & Therapy, 2021 - Springer
Background Sjögren's syndrome (SS) is a chronic, systemic autoimmune disorder
characterized by sicca syndrome and/or systemic manifestations. The disease severely …

Extracellular vesicles and asthma—More than just a co-existence

B Alashkar Alhamwe, DP Potaczek, S Miethe… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are membranous structures, which are secreted by almost every
cell type analyzed so far. In addition to their importance for cell-cell communication under …

Insight into salivary gland aquaporins

C D'Agostino, OA Elkashty, C Chivasso, J Perret… - Cells, 2020 - mdpi.com
The main role of salivary glands (SG) is the production and secretion of saliva, in which
aquaporins (AQPs) play a key role by ensuring water flow. The AQPs are transmembrane …

Mesenchymal stem cell therapy in aqueous deficient dry eye disease

M Møller‐Hansen - Acta Ophthalmologica, 2023 - Wiley Online Library
Abstract ENGLISH SUMMARY Dry eye disease (DED) is characterized by ocular dryness,
irritation and blurred vision and has a significant impact on the patient's quality of life. This …

Mesenchymal stromal cells for the treatment of ocular autoimmune diseases

JY Oh, RH Lee - Progress in retinal and eye research, 2021 - Elsevier
Mesenchymal stromal cells, commonly referred to as MSCs, have emerged as a promising
cell-based therapy for a range of autoimmune diseases thanks to several therapeutic …

Research status and future prospects of extracellular vesicles in primary Sjögren's syndrome

J Zhao, Q An, X Zhu, B Yang, X Gao, Y Niu… - Stem Cell Research & …, 2022 - Springer
Primary Sjögren's syndrome (pSS) is a diffuse connective tissue disease characterized by
the invasion of exocrine glands such as lacrimal and salivary glands, abnormal proliferation …

Trends in salivary gland tissue engineering: from stem cells to secretome and organoid bioprinting

A Chansaenroj, S Yodmuang… - Tissue Engineering Part B …, 2021 - liebertpub.com
Xerostomia or dry mouth are commonly diagnosed in head and neck cancer patients due to
salivary gland (SG) epithelial injury after radiotherapy. Regenerative medicine has fetched …

Treatment of Sjögren's syndrome with mesenchymal stem cells: a systematic review

N Chihaby, M Orliaguet, L Le Pottier, JO Pers… - International journal of …, 2021 - mdpi.com
Mesenchymal stem cells (MSCs) are ubiquitous in the human body. Mesenchymal stem
cells were initially isolated from bone marrow and later from other organs such as fatty …