[HTML][HTML] Calcium-based biomaterials for diagnosis, treatment, and theranostics

C Qi, J Lin, LH Fu, P Huang - Chemical Society Reviews, 2018 - pubs.rsc.org
Calcium-based (CaXs) biomaterials including calcium phosphates, calcium carbonates,
calcium silicate and calcium fluoride have been widely utilized in the biomedical field owing …

Biomolecule-assisted green synthesis of nanostructured calcium phosphates and their biomedical applications

C Qi, S Musetti, LH Fu, YJ Zhu, L Huang - Chemical Society Reviews, 2019 - pubs.rsc.org
Calcium phosphates (CaPs) are ubiquitous in nature and vertebrate bones and teeth, and
have high biocompatibility and promising applications in various biomedical fields …

Nano codelivery of oxaliplatin and folinic acid achieves synergistic chemo-immunotherapy with 5-fluorouracil for colorectal cancer and liver metastasis

J Guo, Z Yu, M Das, L Huang - ACS nano, 2020 - ACS Publications
FOLFOX, the combinational strategy of folinic acid (FnA), 5-fluorouracil (5-Fu), and
oxaliplatin (OxP), has been used as standard treatment of colorectal cancer (CRC) for …

Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and …

J Guo, Z Yu, D Sun, Y Zou, Y Liu, L Huang - Molecular Cancer, 2021 - Springer
Background FOLFOX is a combinational regimen of folinic acid (FnA, FOL), fluorouracil (5-
Fu, F) and oxaliplatin (OxP, OX), and has been long considered as the standard treatment of …

Quercetin remodels the tumor microenvironment to improve the permeation, retention, and antitumor effects of nanoparticles

K Hu, L Miao, TJ Goodwin, J Li, Q Liu, L Huang - ACS nano, 2017 - ACS Publications
Our previous work demonstrated that Wnt16 expression in cisplatin-damaged tumor-
associated fibroblasts is a key factor contributing to cisplatin resistance in malignancies …

Nanoformulations for combination or cascade anticancer therapy

L Miao, S Guo, CM Lin, Q Liu, L Huang - Advanced drug delivery reviews, 2017 - Elsevier
Nanoparticle drug formulations have been extensively investigated, developed, and in some
cases, approved by the Food and Drug Administration (FDA). Synergistic combinations of …

Acyclovir in the treatment of herpes viruses–a review

K Kłysik, A Pietraszek, A Karewicz… - Current medicinal …, 2020 - ingentaconnect.com
Background: Herpes Simplex (HSV) viruses are widely spread, highly contagious human
pathogens. The statistics indicate that 50-90% of adults worldwide are seropositive for these …

Gemcitabine nanoparticles promote antitumor immunity against melanoma

Y Zhang, X Bush, B Yan, JA Chen - Biomaterials, 2019 - Elsevier
Myeloid-derived suppressor cells (MDSCs) promote tumor-mediated immunosuppression
and cancer progression. Gemcitabine (Gem) is a MDSC-depleting chemotherapeutic agent; …

Critical review of synthesis, toxicology and detection of acyclovir

YP Wei, LY Yao, YY Wu, X Liu, LH Peng, YL Tian… - Molecules, 2021 - mdpi.com
Acyclovir (ACV) is an effective and selective antiviral drug, and the study of its toxicology and
the use of appropriate detection techniques to control its toxicity at safe levels are extremely …

Surface engineering of nanomaterials with phospholipid-polyethylene glycol-derived functional conjugates for molecular imaging and targeted therapy

D Zhang, J Zhang - Biomaterials, 2020 - Elsevier
In recent years, phospholipid-polyethylene glycol-derived functional conjugates have been
widely employed to decorate different nanomaterials, due to their excellent biocompatibility …