NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders
CG Lau, RS Zukin - Nature Reviews Neuroscience, 2007 - nature.com
The number and subunit composition of synaptic N-methyl-d-aspartate receptors (NMDARs)
are not static, but change in a cell-and synapse-specific manner during development and in …
are not static, but change in a cell-and synapse-specific manner during development and in …
Regulation of NMDA glutamate receptor functions by the GluN2 subunits
The N‐methyl‐D‐aspartate receptors (NMDARs) are ionotropic glutamate receptors that
mediate the flux of calcium (Ca2+) into the post‐synaptic compartment. Ca2+ influx …
mediate the flux of calcium (Ca2+) into the post‐synaptic compartment. Ca2+ influx …
The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2
The NMDA receptor (NMDAR) is a component of excitatory synapses and a key participant
in synaptic plasticity. We investigated the role of two domains in the C terminus of the NR2B …
in synaptic plasticity. We investigated the role of two domains in the C terminus of the NR2B …
Dynamic aspects of CNS synapse formation
AK McAllister - Annu. Rev. Neurosci., 2007 - annualreviews.org
The mammalian central nervous system (CNS) requires the proper formation of exquisitely
precise circuits to function correctly. These neuronal circuits are assembled during …
precise circuits to function correctly. These neuronal circuits are assembled during …
Rapid bidirectional switching of synaptic NMDA receptors
C Bellone, RA Nicoll - Neuron, 2007 - cell.com
Synaptic NMDA-type glutamate receptors (NMDARs) play important roles in synaptic
plasticity, brain development, and pathology. In the last few years, the view of NMDARs as …
plasticity, brain development, and pathology. In the last few years, the view of NMDARs as …
Homeostatic plasticity and NMDA receptor trafficking
I Pérez-Otaño, MD Ehlers - Trends in neurosciences, 2005 - cell.com
Learning, memory and brain development are associated with long-lasting modifications of
synapses that are guided by specific patterns of neuronal activity. Such modifications …
synapses that are guided by specific patterns of neuronal activity. Such modifications …
Organelles and trafficking machinery for postsynaptic plasticity
MJ Kennedy, MD Ehlers - Annu. Rev. Neurosci., 2006 - annualreviews.org
Neurons are among the largest and most complex cells in the body. Their immense size and
intricate geometry pose many unique cell-biological problems. How is dendritic architecture …
intricate geometry pose many unique cell-biological problems. How is dendritic architecture …
Organization of NMDA receptors at extrasynaptic locations
RS Petralia, YX Wang, F Hua, Z Yi, A Zhou, L Ge… - Neuroscience, 2010 - Elsevier
NMDA receptors are found in neurons both at synapses and in extrasynaptic locations.
Extrasynaptic locations are poorly characterized. Here we used preembedding …
Extrasynaptic locations are poorly characterized. Here we used preembedding …
NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus
RA Al-Hallaq, TP Conrads, TD Veenstra… - Journal of …, 2007 - Soc Neuroscience
Subunit composition of NMDA receptors (NMDARs) determines a range of physiological
properties, downstream signaling effects, and binding partners. Differential localization of …
properties, downstream signaling effects, and binding partners. Differential localization of …
Mechanisms underlying NMDA receptor synaptic/extrasynaptic distribution and function
CM Gladding, LA Raymond - Molecular and Cellular Neuroscience, 2011 - Elsevier
Research over the last few decades has shaped our understanding of the crucial
involvement of the N-methyl-d-aspartate receptor (NMDAR) in mediating excitatory synaptic …
involvement of the N-methyl-d-aspartate receptor (NMDAR) in mediating excitatory synaptic …