Embryonic cells grow in environments that provide a plethora of physical cues, including
mechanical forces that shape the development of the entire embryo. Despite their …

The potential of perinatal tissues to provide cellular populations to be used in different
applications of regenerative medicine is well established. Recently, the efforts of …

Current understandings of cell specification in early mammalian pre-implantation
development are based mainly on mouse studies. The first lineage differentiation event …

During mouse pre-implantation development, the formation of the blastocoel, a fluid-filled
lumen, breaks the radial symmetry of the blastocyst. The factors that control the formation …

Mechanical forces are known to be important in mammalian blastocyst formation; however,
due to limited tools, specific force inputs and how they relay to first cell fate control of inner …

STUDY QUESTION Which processes and transcription factors specify the first and second
lineage segregation events during human preimplantation development? SUMMARY …

The objective of this study was to evaluate the time of blastulation monitored by time-lapse
technology to predict in vitro viability of bovine blastocysts. This technology can be a …

For a successful pregnancy to occur, a predecidualized receptive endometrium must be
invaded by placental differentiated cells (extravillous trophoblast cells (EVTs)) and, at the …

During preimplantation development, the human embryo forms the blastocyst, the structure
enabling uterine implantation. The blastocyst consists of an epithelial envelope, the …

The blastocyst is a conserved stage and distinct milestone in the development of the
mammalian embryo. Blastocyst stage embryos comprise three cell lineages which arise …