Pectins are dietary fibers with different structural characteristics. Specific pectin structures
can influence the gastrointestinal immune barrier by directly interacting with immune cells or …

Galectin 3 is a member of a family of β-galactoside binding proteins and has emerged as an
important regulator of diverse functions critical in cancer biology including apoptosis …

Removal of damaged organelles via the process of selective autophagy constitutes a major
form of cellular quality control. Damaged organelles are recognized by a dedicated …

Several cell surface molecules including signalling receptors are internalized by clathrin-
independent endocytosis. How this process is initiated, how cargo proteins are sorted and …

How endocytic pits are built in clathrin-and caveolin-independent endocytosis still remains
poorly understood. Recent insight suggests that different forms of clathrin-independent …

Galectins are β‐galcotosid‐binding lectins. The function of galectins varies with their tissue‐
specific and subcellular location, and their binding to carbohydrates makes them key players …

Idiopathic pulmonary fibrosis (IPF) is a fatal interstitial lung disease with limited therapeutic
options. Current evidence suggests that IPF may be initiated by repeated epithelial injuries …

Many functions of galectin-3 entail binding of its carbohydrate recognition site to glycans of a
glycoprotein, resulting in cross-linking thought to be mediated by its N-terminal …

Aims Acute myocardial infarction (MI) causes inflammation, collagen deposition, and
reparative fibrosis in response to myocyte death and, subsequently, a pathological …

Rationale: Galectin-3 (Gal-3) drives fibrosis during chronic lung injury, however, its role in
acute lung injury (ALI) remains unknown. Effective pharmacological therapies available for …