The Wnt/β-catenin signaling pathway plays important roles in embryonic development and
tissue homeostasis. Wnt signaling is induced, and β-catenin is activated, associated with the …

Epithelial-mesenchymal transition (EMT) is defined as a process in which differentiated
epithelial cells undergo phenotypic transformation into myofibroblasts capable of producing …

Background Non-small cell lung carcinoma (NSCLC) is a type lung cancer with high
malignant behaviors. MicroRNAs (miRNAs) are known to be involved in progression of …

Aims Cyclophosphamide is an alkylating agent with vast arrays of therapeutic activity.
Currently, its medical use is limited due to its numerous adverse events, including …

Pentosan polysulfate (PPS), a small semi-synthetic highly sulfated heparan sulfate (HS)-like
molecule, shares many of the interactive properties of HS. The aim of this review was to …

Kidney inflammation contributes to the progression of chronic kidney disease (CKD).
Modulation of Toll-like receptor 4 (TLR4) signaling is a potential therapeutic strategy for this …

Tanshinone IIA attenuates high glucose-induced epithelial-to-mesenchymal transition in HK-2
cells through VDR/Wnt/b-catenin sig Page 1 FOLIA HISTOCHEMICA ET CYTOBIOLOGICA …

Lung cancer is recognized as the leading cause of cancer-related death worldwide, with non-
small cell lung cancer (NSCLC) being the predominant subtype, accounting for …

Background Renal fibrosis is the late stage of many chronic kidney diseases (CKD).
Clinically, there is almost no effective treatment for renal fibrosis except dialysis. Renshen …

Background Myocardial infarction (MI) leads to enhanced activity of cardiac fibroblasts (CFs)
and abnormal deposition of extracellular matrix proteins, resulting in cardiac fibrosis …