Gene-environment interactions in psychiatry: recent evidence and clinical implications
Abstract Purpose of Review We identify the recent evidence for gene-by-environment
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …
Moving beyond the mean: Promising research pathways to support a precision medicine approach to hormonal contraception
SE Hill, S Mengelkoch - Frontiers in Neuroendocrinology, 2023 - Elsevier
Women's psychological and behavioral responses to hormonal contraceptive (HC) treatment
can be highly variable. One of the great challenges to researchers seeking to improve the …
can be highly variable. One of the great challenges to researchers seeking to improve the …
[HTML][HTML] FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues …
A Cattaneo, N Cattane, C Malpighi, D Czamara… - Molecular …, 2018 - nature.com
To date, gene-environment (GxE) interaction studies in depression have been limited to
hypothesis-based candidate genes, since genome-wide (GWAS)-based GxE interaction …
hypothesis-based candidate genes, since genome-wide (GWAS)-based GxE interaction …
Attempted suicide and oxytocin-related gene polymorphisms
MS Parris, MF Grunebaum, HC Galfalvy… - Journal of affective …, 2018 - Elsevier
Background Oxytocin may moderate prosocial behaviors, but has also been implicated in
negative mental health outcomes. A single-nucleotide polymorphism (SNP) of the oxytocin …
negative mental health outcomes. A single-nucleotide polymorphism (SNP) of the oxytocin …
Possible oxytocin-related biomarkers in anxiety and mood disorders
S Yoon, YK Kim - Progress in Neuro-Psychopharmacology and …, 2022 - Elsevier
Anxiety and mood disorders are prevalent, disabling, and frequently difficult to treat. Such
disorders are often comorbid and share similar characteristics. For more accurate diagnosis …
disorders are often comorbid and share similar characteristics. For more accurate diagnosis …
Social anxiety is associated with greater peripheral oxytocin reactivity to psychosocial stress
To date, it has been difficult to establish reliable biomarkers associated with specific forms of
psychopathology. Social anxiety, for example, is associated with inconsistent biological …
psychopathology. Social anxiety, for example, is associated with inconsistent biological …
Oxytocin and social sensitivity: gene polymorphisms in relation to depressive symptoms and suicidal ideation
RJ McQuaid, OA McInnis, K Matheson… - Frontiers in human …, 2016 - frontiersin.org
Although the neuropeptide oxytocin has been associated with enhanced prosocial
behaviors, it has also been linked to aggression and mental health disorders. Thus, it was …
behaviors, it has also been linked to aggression and mental health disorders. Thus, it was …
The cortisol awakening response (CAR) interacts with acute interpersonal stress to prospectively predict depressive symptoms among early adolescent girls
CB Stroud, S Vrshek-Shallhorn, EM Norkett… - …, 2019 - Elsevier
The cortisol awakening response (CAR) has been shown to prospectively predict
depression, but it remains unresolved whether a greater CAR predicts risk independently of …
depression, but it remains unresolved whether a greater CAR predicts risk independently of …
Oxytocin and anxiety disorders: translational and therapeutic aspects
WJ Naja, MP Aoun - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review This review aims to evaluate the most recent literature
examining the oxytocin (OXT) system's role in human anxiety by surveying various fields of …
examining the oxytocin (OXT) system's role in human anxiety by surveying various fields of …
[HTML][HTML] Genetic variation in the oxytocin system and its link to social motivation in human infants
KM Krol, N Namaky, MV Monakhov, P San Lai… - …, 2021 - Elsevier
Frontal brain asymmetry has been linked to motivational processes in infants and adults,
with left lateralization reflecting motivation to approach and right lateralization reflecting …
with left lateralization reflecting motivation to approach and right lateralization reflecting …