Gene-environment interactions in psychiatry: recent evidence and clinical implications

RJ Musci, JL Augustinavicius, H Volk - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review We identify the recent evidence for gene-by-environment
interaction studies in relation to psychiatric disorders. We focus on the key genotypic data as …

Moving beyond the mean: Promising research pathways to support a precision medicine approach to hormonal contraception

SE Hill, S Mengelkoch - Frontiers in Neuroendocrinology, 2023 - Elsevier
Women's psychological and behavioral responses to hormonal contraceptive (HC) treatment
can be highly variable. One of the great challenges to researchers seeking to improve the …

[HTML][HTML] FoxO1, A2M, and TGF-β1: three novel genes predicting depression in gene X environment interactions are identified using cross-species and cross-tissues …

A Cattaneo, N Cattane, C Malpighi, D Czamara… - Molecular …, 2018 - nature.com
To date, gene-environment (GxE) interaction studies in depression have been limited to
hypothesis-based candidate genes, since genome-wide (GWAS)-based GxE interaction …

Attempted suicide and oxytocin-related gene polymorphisms

MS Parris, MF Grunebaum, HC Galfalvy… - Journal of affective …, 2018 - Elsevier
Background Oxytocin may moderate prosocial behaviors, but has also been implicated in
negative mental health outcomes. A single-nucleotide polymorphism (SNP) of the oxytocin …

Possible oxytocin-related biomarkers in anxiety and mood disorders

S Yoon, YK Kim - Progress in Neuro-Psychopharmacology and …, 2022 - Elsevier
Anxiety and mood disorders are prevalent, disabling, and frequently difficult to treat. Such
disorders are often comorbid and share similar characteristics. For more accurate diagnosis …

Social anxiety is associated with greater peripheral oxytocin reactivity to psychosocial stress

BA Tabak, D Rosenfield, CS Sunahara, T Alvi… - …, 2022 - Elsevier
To date, it has been difficult to establish reliable biomarkers associated with specific forms of
psychopathology. Social anxiety, for example, is associated with inconsistent biological …

Oxytocin and social sensitivity: gene polymorphisms in relation to depressive symptoms and suicidal ideation

RJ McQuaid, OA McInnis, K Matheson… - Frontiers in human …, 2016 - frontiersin.org
Although the neuropeptide oxytocin has been associated with enhanced prosocial
behaviors, it has also been linked to aggression and mental health disorders. Thus, it was …

The cortisol awakening response (CAR) interacts with acute interpersonal stress to prospectively predict depressive symptoms among early adolescent girls

CB Stroud, S Vrshek-Shallhorn, EM Norkett… - …, 2019 - Elsevier
The cortisol awakening response (CAR) has been shown to prospectively predict
depression, but it remains unresolved whether a greater CAR predicts risk independently of …

Oxytocin and anxiety disorders: translational and therapeutic aspects

WJ Naja, MP Aoun - Current psychiatry reports, 2017 - Springer
Abstract Purpose of Review This review aims to evaluate the most recent literature
examining the oxytocin (OXT) system's role in human anxiety by surveying various fields of …

[HTML][HTML] Genetic variation in the oxytocin system and its link to social motivation in human infants

KM Krol, N Namaky, MV Monakhov, P San Lai… - …, 2021 - Elsevier
Frontal brain asymmetry has been linked to motivational processes in infants and adults,
with left lateralization reflecting motivation to approach and right lateralization reflecting …