Polymeric micelles in cancer therapy: State of the art
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …
Formulation of poloxamers for drug delivery
AM Bodratti, P Alexandridis - Journal of functional biomaterials, 2018 - mdpi.com
Poloxamers, also known as Pluronics®, are block copolymers of poly (ethylene oxide)(PEO)
and poly (propylene oxide)(PPO), which have an amphiphilic character and useful …
and poly (propylene oxide)(PPO), which have an amphiphilic character and useful …
Advances in the therapeutic delivery and applications of functionalized Pluronics: A critical review
Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …
Amphiphilic block copolymers in drug delivery: Advances in formulation structure and performance
AM Bodratti, P Alexandridis - Expert opinion on drug delivery, 2018 - Taylor & Francis
Introduction: Nanostructured delivery vehicles can address key challenges facing drug
delivery, including the lipophilic nature of therapeutic compounds and their effective …
delivery, including the lipophilic nature of therapeutic compounds and their effective …
Pluronic-based nanovehicles: Recent advances in anticancer therapeutic applications
I Jarak, CL Varela, ET da Silva, FFM Roleira… - European Journal of …, 2020 - Elsevier
Pluronics are a class of amphiphilic tri-block copolymers with wide pharmaceutical
applicability. In the past decades, the ability to form biocompatible nanosized micelles was …
applicability. In the past decades, the ability to form biocompatible nanosized micelles was …
Curcumin in the treatment of liver cancer: From mechanisms of action to nanoformulations
SI Shelash Al‐Hawary… - Phytotherapy …, 2023 - Wiley Online Library
Liver cancer is the sixth most prevalent cancer and ranks third in cancer‐related death, after
lung and colorectal cancer. Various natural products have been discovered as alternatives …
lung and colorectal cancer. Various natural products have been discovered as alternatives …
Phytotherapy and nutritional supplements on breast cancer
CM Lopes, A Dourado, R Oliveira - BioMed research …, 2017 - Wiley Online Library
Breast cancer is the most frequent type of nonskin malignancy among women worldwide. In
general, conventional cancer treatment options (ie, surgery, radiotherapy, chemotherapy …
general, conventional cancer treatment options (ie, surgery, radiotherapy, chemotherapy …
CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage
JB Hu, SJ Li, XQ Kang, J Qi, JH Wu, XJ Wang… - Carbohydrate …, 2018 - Elsevier
Based on the abnormally increased expression of CD44 receptors on renal tubule epithelial
cells during ischemia/reperfusion-induced acute kidney injury (AKI), we developed a …
cells during ischemia/reperfusion-induced acute kidney injury (AKI), we developed a …
Inulin-pluronic-stearic acid based double folded nanomicelles for pH-responsive delivery of resveratrol
Herein, we introduce a novel amphiphilic bioconjugate (INU-F68-SA), synthesized by
functionalization of pluronic F68 with a polysaccharide inulin (INU) and a lipid stearic acid …
functionalization of pluronic F68 with a polysaccharide inulin (INU) and a lipid stearic acid …
pH-sensitive micelles based on acid-labile pluronic F68–curcumin conjugates for improved tumor intracellular drug delivery
Curcumin (Cur) is a highly pleiotropic anticancer agent that inhibits cell proliferation and
induces apoptosis in cancer cells. A variety of nano-systems constituted by polymer–drug …
induces apoptosis in cancer cells. A variety of nano-systems constituted by polymer–drug …