Polymeric micelles in cancer therapy: State of the art

B Ghosh, S Biswas - Journal of Controlled Release, 2021 - Elsevier
In recent years, polymeric micelles have been extensively utilized in pre-clinical studies for
delivering poorly soluble chemotherapeutic agents in cancer. Polymeric micelles are formed …

Formulation of poloxamers for drug delivery

AM Bodratti, P Alexandridis - Journal of functional biomaterials, 2018 - mdpi.com
Poloxamers, also known as Pluronics®, are block copolymers of poly (ethylene oxide)(PEO)
and poly (propylene oxide)(PPO), which have an amphiphilic character and useful …

Advances in the therapeutic delivery and applications of functionalized Pluronics: A critical review

P Singla, S Garg, J McClements, O Jamieson… - Advances in Colloid and …, 2022 - Elsevier
Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …

Amphiphilic block copolymers in drug delivery: Advances in formulation structure and performance

AM Bodratti, P Alexandridis - Expert opinion on drug delivery, 2018 - Taylor & Francis
Introduction: Nanostructured delivery vehicles can address key challenges facing drug
delivery, including the lipophilic nature of therapeutic compounds and their effective …

Pluronic-based nanovehicles: Recent advances in anticancer therapeutic applications

I Jarak, CL Varela, ET da Silva, FFM Roleira… - European Journal of …, 2020 - Elsevier
Pluronics are a class of amphiphilic tri-block copolymers with wide pharmaceutical
applicability. In the past decades, the ability to form biocompatible nanosized micelles was …

Curcumin in the treatment of liver cancer: From mechanisms of action to nanoformulations

SI Shelash Al‐Hawary… - Phytotherapy …, 2023 - Wiley Online Library
Liver cancer is the sixth most prevalent cancer and ranks third in cancer‐related death, after
lung and colorectal cancer. Various natural products have been discovered as alternatives …

Phytotherapy and nutritional supplements on breast cancer

CM Lopes, A Dourado, R Oliveira - BioMed research …, 2017 - Wiley Online Library
Breast cancer is the most frequent type of nonskin malignancy among women worldwide. In
general, conventional cancer treatment options (ie, surgery, radiotherapy, chemotherapy …

CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage

JB Hu, SJ Li, XQ Kang, J Qi, JH Wu, XJ Wang… - Carbohydrate …, 2018 - Elsevier
Based on the abnormally increased expression of CD44 receptors on renal tubule epithelial
cells during ischemia/reperfusion-induced acute kidney injury (AKI), we developed a …

Inulin-pluronic-stearic acid based double folded nanomicelles for pH-responsive delivery of resveratrol

AK Jangid, K Patel, P Jain, S Patel, N Gupta… - Carbohydrate …, 2020 - Elsevier
Herein, we introduce a novel amphiphilic bioconjugate (INU-F68-SA), synthesized by
functionalization of pluronic F68 with a polysaccharide inulin (INU) and a lipid stearic acid …

pH-sensitive micelles based on acid-labile pluronic F68–curcumin conjugates for improved tumor intracellular drug delivery

XB Fang, JM Zhang, X Xie, D Liu, CW He… - International Journal of …, 2016 - Elsevier
Curcumin (Cur) is a highly pleiotropic anticancer agent that inhibits cell proliferation and
induces apoptosis in cancer cells. A variety of nano-systems constituted by polymer–drug …