Role of the PE/PPE family in host–pathogen interactions and prospects for anti-tuberculosis vaccine and diagnostic tool design
J Qian, R Chen, H Wang, X Zhang - Frontiers in cellular and infection …, 2020 - frontiersin.org
The pe/ppe genes are found in pathogenic, slow-growing Mycobacterium tuberculosis and
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …
other M. tuberculosis complex (MTBC) species. These genes are considered key factors in …
Immunological effects of the PE/PPE family proteins of Mycobacterium tuberculosis and related vaccines
F Guo, J Wei, Y Song, B Li, Z Qian, X Wang… - Frontiers in …, 2023 - frontiersin.org
Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis
(Mtb), and its incidence and mortality are increasing. The BCG vaccine was developed in the …
(Mtb), and its incidence and mortality are increasing. The BCG vaccine was developed in the …
The Mycobacterium tuberculosis PE_PGRS Protein Family Acts as an Immunological Decoy to Subvert Host Immune Response
Mycobacterium tuberculosis (M. tb) is a successful pathogen that can reside within the
alveolar macrophages of the host and can survive in a latent stage. The pathogen has …
alveolar macrophages of the host and can survive in a latent stage. The pathogen has …
Rv3539 (PPE63) of Mycobacterium Tuberculosis Promotes Survival of Mycobacterium Smegmatis in Human Macrophages Cell Line via Cell Wall Modulation of …
The modulation of host's immune response plays an important role in the intracellular
survival of Mycobacterium tuberculosis. The intracellular pathogen counteracts …
survival of Mycobacterium tuberculosis. The intracellular pathogen counteracts …
Cell wall and immune modulation by Rv1800 (PPE28) helps M. smegmatis to evade intracellular killing
Rv1800 is predicted as PPE family protein found in pathogenic mycobacteria only. Under
acidic stress, the rv1800 gene was expressed in M. tuberculosis H37Ra. In-silico study …
acidic stress, the rv1800 gene was expressed in M. tuberculosis H37Ra. In-silico study …
Long-Term Immunogenicity and In Vitro Prophylactic Protective Efficacy of M. tuberculosis Fusion Protein DR2 Combined with Liposomal Adjuvant DIMQ as a …
L Mao, J Du, X Wang, L Xu, Y Zhang, Q Sun… - ACS Infectious …, 2023 - ACS Publications
The resuscitation of dormant Mycobacterium tuberculosis is an important cause of adult
tuberculosis (TB) transmission. According to the interaction mechanism between M …
tuberculosis (TB) transmission. According to the interaction mechanism between M …
Mycobacterium tuberculosis YrbE3A Promotes Host Innate Immune Response by Targeting NF-κB/JNK Signaling
J Wang, X Zhu, Y Peng, T Zhu, H Liu, Y Zhu, X Xiong… - Microorganisms, 2020 - mdpi.com
Mycobacterium tuberculosis is considered a successful pathogen with multiple strategies to
undermine host immunity. The YrbE3A is encoded by Rv1964 within the RD15 region …
undermine host immunity. The YrbE3A is encoded by Rv1964 within the RD15 region …
The PE and PPE Family Proteins of Mycobacterium tuberculosis: What they Are Up To?
R Pal, F Nazar, S Mukhopadhyay - Mycobacterium tuberculosis: Molecular …, 2019 - Springer
An ebb and flow journey of over 125 years since the discovery of Mycobacterium
tuberculosis (M. tb), the causative agent of tuberculosis (TB), clearly established it as an …
tuberculosis (M. tb), the causative agent of tuberculosis (TB), clearly established it as an …
Impact of the elderly lung mucosa on Mycobacterium tuberculosis metabolic adaptation during infection of alveolar epithelial cells
AM Olmo-Fontánez, A Allué-Guardia… - bioRxiv, 2024 - biorxiv.org
Background: Tuberculosis (TB) is one of the top leading causes of death due to a single
infectious agent. Upon infection, Mycobacterium tuberculosis (M. tb) is deposited in the …
infectious agent. Upon infection, Mycobacterium tuberculosis (M. tb) is deposited in the …
[HTML][HTML] Identification and characterization of antigenic and immunomodulatory properties of PE and PPE proteins of Mycobacterium tuberculosis
M García Bengoa - 2023 - elib.tiho-hannover.de
Tuberkulose (TB) stellt nach wie vor eine erhebliche globale Gesundheitsbelastung dar, von
der jedes Jahr Millionen von Menschen betroffen sind und die zahlreiche Todesfälle …
der jedes Jahr Millionen von Menschen betroffen sind und die zahlreiche Todesfälle …