Chemi-and bioluminescence of cyclic peroxides

M Vacher, I Fdez. Galván, BW Ding, S Schramm… - Chemical …, 2018 - ACS Publications
Bioluminescence is a phenomenon that has fascinated mankind for centuries. Today the
phenomenon and its sibling, chemiluminescence, have impacted society with a number of …

Spectrochemistry of firefly bioluminescence

MB Al-Handawi, S Polavaram, A Kurlevskaya… - Chemical …, 2022 - ACS Publications
The chemical reactions underlying the emission of light in fireflies and other bioluminescent
beetles are some of the most thoroughly studied processes by scientists worldwide. Despite …

Biosynthesis of nonribosomal peptides

R Finking, MA Marahiel - Annu. Rev. Microbiol., 2004 - annualreviews.org
▪ Abstract Bacteria and fungi use large multifunctional enzymes, the so-called nonribosomal
peptide synthetases (NRPSs), to produce peptides of broad structural and biological activity …

The evolution of the phenylpropanoid pathway entailed pronounced radiations and divergences of enzyme families

S de Vries, JMR Fürst‐Jansen, I Irisarri… - The Plant …, 2021 - Wiley Online Library
Land plants constantly respond to fluctuations in their environment. Part of their response is
the production of a diverse repertoire of specialized metabolites. One of the foremost …

Mechanisms of actions of inhaled anesthetics

JA Campagna, KW Miller… - New England Journal of …, 2003 - Mass Medical Soc
“Suffering so great as I underwent cannot be expressed in words... but the blank whirlwind of
emotion, the horror of great darkness, and the sense of desertion by God and man, which …

Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?

PD Dobson, DB Kell - Nature reviews Drug discovery, 2008 - nature.com
It is generally thought that many drug molecules are transported across biological
membranes via passive diffusion at a rate related to their lipophilicity. However, the types of …

Binding of the general anesthetics propofol and halothane to human serum albumin: high resolution crystal structures

AA Bhattacharya, S Curry, NP Franks - Journal of Biological Chemistry, 2000 - ASBMB
Human serum albumin (HSA) is one of the most abundant proteins in the circulatory system
and plays a key role in the transport of fatty acids, metabolites, and drugs. For many drugs …

Structural basis for the spectral difference in luciferase bioluminescence

T Nakatsu, S Ichiyama, J Hiratake, A Saldanha… - Nature, 2006 - nature.com
Fireflies communicate with each other by emitting yellow-green to yellow-orange brilliant
light. The bioluminescence reaction, which uses luciferin, Mg-ATP and molecular oxygen to …

The origin, diversity, and structure function relationships of insect luciferases

VR Viviani - Cellular and Molecular Life Sciences CMLS, 2002 - Springer
Luciferases are the enzymes that catalyze the reactions that produce light in
bioluminescence. Whereas the oxidative mechanism which leads to light emission is similar …

General anaesthetic actions on ligand-gated ion channels

MD Krasowski, NL Harrison - Cellular and Molecular Life Sciences CMLS, 1999 - Springer
The molecular mechanisms of general anaesthetics have remained largely obscure since
their introduction into clinical practice just over 150 years ago. This review describes the …