Electro-polymerized poly-methyldopa as a novel synthetic mussel-inspired molecularly imprinted polymeric sensor for darifenacin: computational and experimental …

M Wadie, EM Abdel-Moety, MR Rezk… - Applied Materials …, 2022 - Elsevier
The massive progress in molecularly imprinted polymers has encouraged the inclusion of
new molecules as functional monomers to attain more selective recognition. Herein and for …

Univariate and multivariate determination of dapagliflozin and saxagliptin in bulk and dosage form

MM Elhassan, AM Mahmoud… - Journal of AOAC …, 2023 - academic.oup.com
Background Dapagliflozin is a sodium glucose cotransporter-II inhibitor while saxagliptin is a
dipeptidyl peptidase-4 inhibitor. Both are used to manage type 2 diabetes mellitus. Objective …

In situ sensing of the neurotransmitter acetylcholine in a dynamic range of 1 nM to 1 mM

MPS Mousavi, MK Abd El-Rahman, AM Mahmoud… - ACS …, 2018 - ACS Publications
The neurotransmitter acetylcholine (ACh) plays a key role in the pathophysiology of brain
disorders such as Alzheimer's disease. Understanding the dynamics of ACh concentration …

Host-Guest Complexation of Oxaliplatin and Para-Sulfonatocalix[n]Arenes for Potential Use in Cancer Therapy

SA Fahmy, F Ponte, IM Fawzy, E Sicilia, U Bakowsky… - Molecules, 2020 - mdpi.com
P-sulfonatocalix [n] arenes have demonstrated a great potential for encapsulation of
therapeutic drugs via host-guest complexation to improve solubility, stability, and …

[HTML][HTML] Supramolecular therapeutics to treat the side effects induced by a depolarizing neuromuscular blocking agent

X Zhang, Q Cheng, L Li, L Shangguan, C Li, S Li… - Theranostics, 2019 - ncbi.nlm.nih.gov
Succinylcholine (Sch) is the only depolarizing neuromuscular blocking agent widely used for
rapid sequence induction in emergency rooms. Unfortunately, a variety of (sometimes lethal) …

Investigation of the host-guest complexation between 4-sulfocalix [4] arene and nedaplatin for potential use in drug delivery

SA Fahmy, F Ponte, MK Abd El-Rahman… - … Acta Part A: Molecular …, 2018 - Elsevier
Macromolecules including macrocyclic species have been reported to have the potential to
encapsulate biologically active compounds such as drugs through host-guest complexation …

Supramolecular neuromuscular blocker inhibition by a pillar [5] arene through aqueous inclusion of rocuronium bromide

DN Shurpik, OA Mostovaya, DA Sevastyanov… - Organic & …, 2019 - pubs.rsc.org
A water-soluble pillar [5] arene, decafunctionalized with thioether and carboxylate
fragments, was synthesized as a structural analogue of Sugammadex. Its ability to restore …

An accessible yarn-based sensor for in-field detection of succinylcholine poisoning

V Ong, NR Cortez, Z Xu, F Amirghasemi… - Chemosensors, 2023 - mdpi.com
Succinylcholine (SUX) is a clinical anesthetic that induces temporary paralysis and is
degraded by endogenous enzymes within the body. In high doses and without respiratory …

Host–guest encapsulation of RIBO with TSC4X: synthesis, characterization, and its application by physicochemical and computational investigations

B Ghosh, N Roy, S Mandal, S Ali, P Bomzan, D Roy… - ACS …, 2023 - ACS Publications
In our present work, we synthesized a new encapsulated complex denoted as RIBO-TSC4X,
which was derived from an important vitamin riboflavin (RIBO) and p-sulfonatothiacalix [4] …

Supramolecular green chemistry; an eco-friendly spectrophotometric approach for determination of non-chromophoric methacholine via host-guest interactions with 4 …

NB ElDin, MK Abd El-Rahman, HE Zaazaa… - Microchemical …, 2021 - Elsevier
Supramolecular chemistry has gained an increasing attention in different disciplines of
pharmaceutical community. Methacholine chloride (MCh) is a parasympathomimetic …