Polymers such as Dacron® and polytetrafluoroethylene (PTFE) have been used in high flow
states with relative success but with limited application at lower flow states. Newer polymers …

The construction of tissue-engineered devices for medical applications is now possible in
vitro using cell culture and bioreactors. Although methods of incorporating them back into …

We have fabricated a hepatic tissue construct using a multilayer photopatterning platform for
embedding cells in hydrogels of complex architecture. We first explored the potential of …

The development of an ideal small-diameter conduit for use in vascular bypass surgery has
yet to be achieved. The ongoing innovation in biomaterial design generates novel conduits …

The ability of the biomimetic peptides YIGSR, PHSRN and RGD to selectively affect
adhesion and migration of human microvascular endothelial cells (MVEC) and vascular …

The clinical utility of a small-caliber vascular graft is still limited, owing to the occlusion of
graft by thrombosis and restenosis. A small-caliber vascular graft (diameter, 2.5 mm) …

A number of vascular therapies could benefit from advanced methods for presentation of
angiogenic growth factors, including growth of endothelium on small caliber vascular grafts …

The migration of human microvascular endothelial cells (hMEC) was measured on a range
of fibronectin gradient slopes. hMEC drift speed increased with increasing gradient slope …

A tissue-engineered small-diameter arterial graft would be of benefit to patients requiring
vascular reconstructive procedures. Our objective was to produce a tissue-engineered …

In patients requiring coronary or peripheral vascular bypass procedures, autogenous arterial
or vein grafts remain as the conduit of choice even in the case of redo patients. It is in this …