[HTML][HTML] Novel biomarkers for diagnosis and monitoring of immune thrombocytopenia

A Allegra, N Cicero, G Mirabile, CM Giorgianni… - International journal of …, 2023 - mdpi.com
Lower-than-normal platelet counts are a hallmark of the acquired autoimmune illness known
as immune thrombocytopenia, which can affect both adults and children. Immune …

Redox control of platelet functions in physiology and pathophysiology

D Pietraforte, R Vona, A Marchesi… - Antioxidants & Redox …, 2014 - liebertpub.com
Significance: An imbalance between the production and the detoxification of reactive oxygen
species and reactive nitrogen species (ROS/RNS) can be implicated in many pathological …

Reduced intracellular antioxidant capacity in platelets contributes to primary immune thrombocytopenia via ROS-NLRP3-caspase-1 pathway

S Wang, Y Liu, G Li, Q Feng, M Hou, J Peng - Thrombosis Research, 2021 - Elsevier
Primary immune thrombocytopenia (ITP) is a common acquired autoimmune hemorrhagic
disease characterized by a low platelet count and increased risk of bleeding. However …

Antioxidant status and oxidative stress in patients with chronic ITP

CQ Jin, HX Dong, PP Cheng, JW Zhou… - Scandinavian …, 2013 - Wiley Online Library
The aim of this study was to establish the antioxidant status and oxidative stress in adult
patients with chronic idiopathic thrombocytopenic purpura (ITP). Eighty‐four patients …

Oxidative stress is predominant in female but not in male patients with autoimmune thrombocytopenia

J Kamhieh-Milz, A Salama - Oxidative medicine and cellular …, 2014 - Wiley Online Library
As the involvement of oxidative stress (OS) in autoimmune thrombocytopenia (AITP) has
been reported, a fast and rapid test for the reliable measurement of OS and antioxidant …

Effect of glucocorticoid treatment on BAFF and APRIL expression in patients with immune thrombocytopenia (ITP)

J Kamhieh-Milz, N Ghosoun, V Sterzer, A Salama - Clinical Immunology, 2018 - Elsevier
Immune thrombocytopenic purpura (ITP) is an idiopathic bleeding disorder. B cell activating
factor (BAFF) and 'A proliferation-inducing ligand'(APRIL) have regulatory effects on B and T …

Identification of novel autoantigens via mass spectroscopy-based antibody-mediated identification of autoantigens (MS-AMIDA) using immune thrombocytopenic …

J Kamhieh-Milz, V Sterzer, H Celik, O Khorramshahi… - Journal of …, 2017 - Elsevier
Immune thrombocytopenic purpura (ITP) is one of the best characterized autoimmune
diseases. Autoantibodies (AABs) against platelet antigens are considered as the diagnostic …

Variations of Redox Balance in Different Stages of Childhood Immune Thrombocytopenic Purpura

RH Medovic, IM Srejovic, MV Medovic… - Thrombosis and …, 2023 - thieme-connect.com
Background Few previous studies indicated the role of oxidative stress in the pathogenesis
of childhood idiopathic thrombocytopenic purpura (ITP), but there are little data regarding …

Oxidant/antioxidant status in children and adolescents with immune thrombocytopenia (ITP) and the role of an adjuvant antioxidant therapy

MS Elalfy, YI Elhenawy, S Deifalla… - Pediatric Blood & …, 2015 - Wiley Online Library
Background Free oxygen radicals might have an adverse effect on platelets which might be
reflected either on its count and/or degree of bleeding severity. Aim To assess oxidant …

[PDF][PDF] Effect of short-term, high-dose methylprednisolone on oxidative stress in children with acute immune thrombocytopenia

M Cura, A Koç, N Aksoy, ZC Özdemir - Blood research, 2016 - synapse.koreamed.org
Background Immune thrombocytopenia (ITP) is the most common cause of acquired
childhood thrombocytopenia and is characterized by increased immune-mediated …