Cholesterol transport revisited: a new turbo mechanism to drive cholesterol excretion

JF de Boer, F Kuipers, AK Groen - Trends in Endocrinology & Metabolism, 2018 - cell.com
A fine-tuned balance between cholesterol uptake and excretion by the body is pivotal to
maintain health and to remain free from the deleterious consequences of cholesterol …

Gut-liver axis

S Zeuzem - International journal of colorectal disease, 2000 - Springer
The gut and the liver are the key organs in nutrient absorption and metabolism. Bile acids,
drugs, and toxins undergo extensive enterohepatic circulation. Bile acids play a major role in …

Biliary and nonbiliary contributions to reverse cholesterol transport

RE Temel, JM Brown - Current opinion in lipidology, 2012 - journals.lww.com
Biliary and nonbiliary contributions to reverse cholesterol... : Current Opinion in Lipidology
Biliary and nonbiliary contributions to reverse cholesterol transport : Current Opinion in …

Serum noncholesterol sterols during inhibition of cholesterol synthesis by statins

TA Miettinen, H Gylling, N Lindbohm… - Journal of Laboratory …, 2003 - Elsevier
We studied changes in serum cholestanol and plant sterols (indexes of cholesterol
absorption) and cholesterol precursors (indexes of cholesterol synthesis) in response to …

Effects of sorghum rice and black rice on genes associated with cholesterol metabolism in hypercholesterolemic mice liver and intestine

H Liu, L Huang, X Pei - Food Science & Nutrition, 2021 - Wiley Online Library
The effects of different proportions of dietary sorghum rice and black rice on the expression
of genes related to cholesterol metabolism in mice liver, intestine, and the characteristics of …

Polymorphisms at the apoB, apoA-I, and cholesteryl ester transfer protein gene loci in patients with gallbladder disease.

T Juvonen, MJ Savolainen, MI Kairaluoma… - Journal of lipid …, 1995 - Elsevier
Alterations in lipoprotein levels are reported to be related to an increased risk of gallstones.
Plasma lipid metabolism is regulated by a number of proteins that are polymorphic in the …

Altered lipid metabolism in apolipoprotein E-deficient mice does not affect cholesterol balance across the liver

F Kuipers, JM Van Ree, MH Hofker, H Wolters… - Hepatology, 1996 - journals.lww.com
Adaptation of cholesterol and bile acid synthesis and of biliary cholesterol secretion
represent key metabolic responses to maintain cholesterol homeostasis and have been …

[PDF][PDF] New insights into the mechanism of bile acid—induced biliary lipid secretion

HJ Verkade, RJ Vonk, F Kuipers - Hepatology, 1995 - Wiley Online Library
The hepatocyte is a polarized cell with a distinct basolateral and an apical (bile canalicular)
domain. Transport processes at the two poles of the cell show a high degree of specifi~ ity.' …

Animal models of human lipid metabolism

KE Suckling, B Jackson - Progress in lipid research, 1993 - Elsevier
Models of human metabolism are of great importance to many areas of biology. This is
perhaps most clearly found in the field of toxicology and drug metabolism where studies in …

Blackcurrant anthocyanins stimulated cholesterol transport via post-transcriptional induction of LDL receptor in Caco-2 cells

B Kim, M Bae, YK Park, H Ma, T Yuan… - European journal of …, 2018 - Springer
Purposes We previously showed that polyphenol-rich blackcurrant extract (BCE) showed a
hypocholesterolemic effect in mice fed a high fat diet. As direct cholesterol removal from the …