Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases

AV Cybulsky - Nature Reviews Nephrology, 2017 - nature.com
Progress has been made in our understanding of the mechanisms of endoplasmic reticulum
(ER) proteostasis, ER stress and the unfolded protein response (UPR), as well as ER stress …

Role of endoplasmic reticulum stress in drug‐induced toxicity

F Foufelle, B Fromenty - Pharmacology research & …, 2016 - Wiley Online Library
Drug‐induced toxicity is a key issue for public health because some side effects can be
severe and life‐threatening. These adverse effects can also be a major concern for the …

Regenerative proliferation of differentiated cells by mTORC 1‐dependent paligenosis

SG Willet, MA Lewis, ZF Miao, D Liu, MD Radyk… - The EMBO …, 2018 - embopress.org
In 1900, Adami speculated that a sequence of context‐independent energetic and structural
changes governed the reversion of differentiated cells to a proliferative, regenerative state …

Endoplasmic reticulum stress in ischemic and nephrotoxic acute kidney injury

M Yan, S Shu, C Guo, C Tang, Z Dong - Annals of medicine, 2018 - Taylor & Francis
Acute kidney injury (AKI) is a medical condition characterized by kidney damage with a rapid
decline of renal function, which is associated with high mortality and morbidity. Recent …

Cadmium exposure triggers mitochondrial dysfunction and oxidative stress in chicken (Gallus gallus) kidney via mitochondrial UPR inhibition and Nrf2-mediated …

J Ge, C Zhang, YC Sun, Q Zhang, MW Lv, K Guo… - Science of the Total …, 2019 - Elsevier
Cadmium (Cd) is a widespread environmental pollutant that accumulates in living systems
and represents a significant global health hazard. Cd poses a toxicity threat to both human …

Maternal obesity: new placental paradigms unfolded

C Brombach, W Tong, DA Giussani - Trends in molecular medicine, 2022 - cell.com
The prevalence of maternal obesity is increasing at an alarming rate, and is providing a
major challenge for obstetric practice. Adverse effects on maternal and fetal health are …

Endoplasmic reticulum stress in kidney function and disease

M Taniguchi, H Yoshida - Current opinion in nephrology and …, 2015 - journals.lww.com
Endoplasmic reticulum stress in kidney function and disease : Current Opinion in Nephrology
and Hypertension Endoplasmic reticulum stress in kidney function and disease : Current …

[HTML][HTML] Ursodeoxycholic acid and 4-phenylbutyrate prevent endoplasmic reticulum stress-induced podocyte apoptosis in diabetic nephropathy

AL Cao, L Wang, X Chen, YM Wang, HJ Guo… - Laboratory …, 2016 - Elsevier
Endoplasmic reticulum (ER) stress, resulting from the accumulation of misfolded and/or
unfolded proteins in ER membranes, is involved in the pathogenesis of diabetic …

The role of endoplasmic reticulum stress in diabetic nephropathy

Y Fan, K Lee, N Wang, JC He - Current diabetes reports, 2017 - Springer
Abstract Purpose of Review Diabetic nephropathy (DN) has become the leading cause of
end-stage renal disease (ESRD) worldwide. Accumulating evidence suggests that …

Ganoderma lucidum polysaccharide peptide prevents renal ischemia reperfusion injury via counteracting oxidative stress

D Zhong, H Wang, M Liu, X Li, M Huang, H Zhou… - Scientific reports, 2015 - nature.com
Ganoderma lucidum polysaccharide peptide (GLPP) scavenges oxygen free radicals that
are a key factor in the pathogenesis of renal ischemia reperfusion injury (RIRI). The aim of …