[HTML][HTML] Microalgae n-3 PUFAs production and use in food and feed industries

M Remize, Y Brunel, JL Silva, JY Berthon, E Filaire - Marine drugs, 2021 - mdpi.com
N-3 polyunsaturated fatty acids (n-3 PUFAs), and especially eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA), are essential compounds for human health. They have …

Scientific Opinion on the update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA (2017–2019)

EFSA Panel on Biological Hazards (BIOHAZ)… - EFSA …, 2020 - Wiley Online Library
The qualified presumption of safety (QPS) was developed to provide a safety pre‐
assessment within EFSA for microorganisms. Strains belonging to QPS taxonomic units (TU …

Duplex structure of double-stranded RNA provides stability against hydrolysis relative to single-stranded RNA

K Zhang, J Hodge, A Chatterjee, TS Moon… - Environmental …, 2021 - ACS Publications
Phosphodiester bonds in the backbones of double-stranded (ds) RNA and single-stranded
(ss) RNA are known to undergo alkaline hydrolysis. Consequently, dsRNA agents used in …

[HTML][HTML] Fed-batch fermentation of mixed carbon source significantly enhances the production of docosahexaenoic acid in Thraustochytriidae sp. PKU# Mn16 by …

H Ye, Y He, Y Xie, B Sen, G Wang - Bioresource technology, 2020 - Elsevier
This study reports comparative evaluation of the growth and DHA productivity of the
thraustochytrid strain Thraustochytriidae PKU# Mn16 fermented with seven different …

[HTML][HTML] Deciphering and engineering the polyunsaturated fatty acid synthase pathway from eukaryotic microorganisms

P Guo, L Dong, F Wang, L Chen… - Frontiers in Bioengineering …, 2022 - frontiersin.org
Polyunsaturated fatty acids (PUFAs) are important nutrients that play important roles in
human health. In eukaryotes, PUFAs can be de novo synthesized through two independent …

Enhancing the accumulation of lipid and docosahexaenoic acid in Schizochytrium sp. by co‐overexpression of phosphopantetheinyl transferase and ω‐3 fatty acid …

J Li, Y Zheng, WQ Yang, ZY Wei, YS Xu… - Biotechnology …, 2023 - Wiley Online Library
Docosahexaenoic acid (DHA) as one of ω‐3 polyunsaturated fatty acids (PUFAs), plays a
key role in brain development, and is widely used in food additives and the pharmaceutical …

Development of a scale-up strategy for fermentative production of docosahexaenoic acid by Schizochytrium sp.

DS Guo, XJ Ji, LJ Ren, GL Li, XM Sun, KQ Chen… - Chemical Engineering …, 2018 - Elsevier
Process scale-up is a critical factor for realizing the industrial-scale production of
docosahexaenoic acid (DHA). To improve the efficiency of scale-up, a strategy based on …

Genetic regulation and fermentation strategy for squalene production in Schizochytrium sp.

Q Yang, Z Xie, X Zheng, K Li, T Lu, Y Lu… - Applied Microbiology …, 2022 - Springer
Squalene, as an important terpenoid, is extensively used in the medicine and health care
fields owing to its functions of anti-oxidation, blood lipid regulation and cancer prevention …

Enhanced saturated fatty acids accumulation in cultures of newly-isolated strains of Schizochytrium sp. and Thraustochytriidae sp. for large-scale biodiesel production

Q Wang, B Sen, X Liu, Y He, Y Xie, G Wang - Science of the Total …, 2018 - Elsevier
Heterotrophic marine protists (Thraustochytrids) have received increasingly global attention
as a renewable, sustainable and alternative source of biodiesel because of their high ability …

Effects of butanol on high value product production in Schizochytrium limacinum B4D1

K Zhang, L Chen, J Liu, F Gao, R He, W Chen… - Enzyme and microbial …, 2017 - Elsevier
Schizochytrium is a microalgae-like fungus and is widely used for producing
docosahexaenoic acid (DHA). It is also a promising source of squalene and carotenoids …