The liver is a central organ in the human body, coordinating several key metabolic roles. The
structure of the liver which consists of the distinctive arrangement of hepatocytes, hepatic …

Hepatic fibrosis is a wound-healing response to various chronic stimuli, including viral
hepatitis B or C infection. Activated myofibroblasts, predominantly derived from the hepatic …

Silymarin, a standardized extract of the milk thistle (Silybum marianum), has a long tradition
as a herbal remedy, and was introduced as a hepatoprotective agent a few years ago …

The immunopathogenic process from hepatitis B virus (HBV) infection to liver fibrosis is
incompletely understood because it lacks an animal model. In this study we observed the …

AIMS: To investigate the feasibility and mechanism of liver damage repair using human
bone marrow mesenchymal stem cells (hBMMSCs), we investigated the potential for …

Fucoidan, a sulfated polysaccharide extracted from brown algae, has a wide range of
biological activities, including anti-inflammatory, anti-viral, and anti-tumor activities. In the …

Liver cirrhosis and hepatocellular carcinomas are major health problems of chronic hepatitis
B virus (HBV) infection. To date, rare model has reproduced liver fibrosis associated with …

In chronic hepatitis B virus (HBV) infection, inflammation-associated cytokines including
proinflammatory cytokines are involved in the development and progression of liver fibrosis …

Schistosomiasis remains a major global public health concern. Currently, the control of this
neglected tropical disease still depends on chemotherapy to reduce the prevalence and …

Autophagy is a very tightly regulated process that is important in many cellular processes
including development, differentiation, survival and homoeostasis. The importance of this …