Bridging animal and human models of exercise-induced brain plasticity
Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …
through which exercise protects and restores the brain. In this feature review, we integrate …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
The neuroprotective effects of exercise: maintaining a healthy brain throughout aging
LM Vecchio, Y Meng, K Xhima, N Lipsman… - Brain …, 2018 - content.iospress.com
Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …
Environmental enrichment and brain repair: harnessing the therapeutic effects of cognitive stimulation and physical activity to enhance experience‐dependent …
AJ Hannan - Neuropathology and applied neurobiology, 2014 - Wiley Online Library
Environmental enrichment (EE) increases levels of novelty and complexity, inducing
enhanced sensory, cognitive and motor stimulation. In wild‐type rodents, EE has been found …
enhanced sensory, cognitive and motor stimulation. In wild‐type rodents, EE has been found …
Is dysregulation of the HPA-axis a core pathophysiology mediating co-morbid depression in neurodegenerative diseases?
There is increasing evidence of prodromal manifestation of neuropsychiatric symptoms in a
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …
variety of neurodegenerative diseases such as Parkinson's disease (PD) and Huntington's …
On the run for hippocampal plasticity
HY Moon, H van Praag - Cold Spring …, 2018 - perspectivesinmedicine.cshlp.org
Accumulating research in rodents and humans indicates that exercise benefits brain function
and may prevent or delay onset of neurodegenerative conditions. In particular, exercise …
and may prevent or delay onset of neurodegenerative conditions. In particular, exercise …
Enhancement of cognitive function in models of brain disease through environmental enrichment and physical activity
This review will provide an overview of the non-drug based approaches that have been
demonstrated to enhance cognitive function of the compromised brain, primarily focussed on …
demonstrated to enhance cognitive function of the compromised brain, primarily focussed on …
Environmental factors as modulators of neurodegeneration: Insights from gene–environment interactions in Huntington's disease
Unlike many other neurodegenerative diseases with established gene–environment
interactions, Huntington's disease (HD) is viewed as a disorder governed by genetics. The …
interactions, Huntington's disease (HD) is viewed as a disorder governed by genetics. The …
The underestimated sex: A review on female animal models of depression
Major depression (MD) is the most common psychiatric disorder, predicted to affect around
264 million people worldwide. Although the etiology of depression remains elusive, the …
264 million people worldwide. Although the etiology of depression remains elusive, the …