Gabapentin for chronic neuropathic pain in adults

PJ Wiffen, S Derry, RF Bell, ASC Rice… - Cochrane Database …, 2017 - cochranelibrary.com
Background Gabapentin is commonly used to treat neuropathic pain (pain due to nerve
damage). This review updates a review published in 2014, and previous reviews published …

Gabapentin for chronic neuropathic pain and fibromyalgia in adults

RA Moore, PJ Wiffen, S Derry… - Cochrane database of …, 2014 - cochranelibrary.com
Background This review is an update of a review published in 2011, itself a major update of
previous reviews published in 2005 and 2000, investigating the effects of gabapentin in …

Neuropathic pain in cancer

MT Fallon - British journal of anaesthesia, 2013 - academic.oup.com
Cancer-related neuropathic pain is common; it can be disease related or related to the acute
or chronic effects of cancer treatment. For example, chemotherapy-induced peripheral …

Combination pharmacotherapy for the treatment of neuropathic pain in adults

LE Chaparro, PJ Wiffen, RA Moore… - Cochrane database of …, 2012 - cochranelibrary.com
Background Pharmacotherapy remains an important modality for the treatment of
neuropathic pain. However, as monotherapy current drugs are associated with limited …

Implications and mechanism of action of gabapentin in neuropathic pain

A Kukkar, A Bali, N Singh, AS Jaggi - Archives of pharmacal research, 2013 - Springer
Gabapentin is an anti-epileptic agent but now it is also recommended as first line agent in
neuropathic pain, particularly in diabetic neuropathy and post herpetic neuralgia. α2δ-1, an …

Pharmacological treatment of neuropathic cancer pain: a comprehensive review of the current literature

A Vadalouca, E Raptis, E Moka, P Zis, P Sykioti… - Pain …, 2012 - Wiley Online Library
Neuropathic cancer pain (NCP), commonly encountered in clinical practice, may be cancer‐
related, namely resulting from nervous system tumor invasion, surgical nerve damage …

Opioids combined with antidepressants or antiepileptic drugs for cancer pain: systematic review and meta-analysis

CM Kane, MR Mulvey, S Wright, C Craigs… - Palliative …, 2018 - journals.sagepub.com
Background: Combining antidepressant or antiepileptic drugs with opioids has resulted in
increased pain relief when used for neuropathic pain in non-cancer conditions. However …

Combination therapy for neuropathic pain: a review of current evidence

Y Vorobeychik, V Gordin, J Mao, L Chen - CNS drugs, 2011 - Springer
Neuropathic pain is a debilitating chronic condition that remains very difficult to treat.
Recently, a number of clinical studies have compared the effectiveness of combination drug …

Combination drug therapy for the management of chronic neuropathic pain

S Boccella, L De Filippis, C Giorgio, L Brandolini… - Biomolecules, 2023 - mdpi.com
Chronic neuropathic pain (NP) is an increasingly prevalent disease and leading cause of
disability which is challenging to treat. Several distinct classes of drugs are currently used for …

Metabolite profiling reveals a connection between aldehyde dehydrogenase 1A3 and GABA metabolism in breast cancer metastasis

ML Dahn, HR Walsh, CA Dean, MA Giacomantonio… - Metabolomics, 2022 - Springer
Abstract Introduction Aldehyde dehydrogenase 1A3 (ALDH1A3) is a cancer stem cell (CSC)
marker and in breast cancer it is associated with triple-negative/basal-like subtypes and …