Inflammatory bowel diseases (IBD), including Crohn's Disease (CD) and Ulcerative Colitis
(UC) are chronic multifactorial disorders which affect the gastrointestinal tract with variable …

Osteogenesis imperfecta (OI) is a disease caused by mutations in different genes resulting
in mild, severe, or lethal forms. With no cure, researchers have investigated the use of cell …

Background Numerous genes, including SOD1, mutated in familial and sporadic
amyotrophic lateral sclerosis (f/sALS) share a role in DNA damage and repair, emphasizing …

Osteogenesis imperfecta (OI) is an uncommon genetic disorder characterized by shortness
of stature, hearing loss, poor bone mass, recurrent fractures, and skeletal abnormalities …

Bone damage leading to bone loss can arise from a wide range of causes, including those
intrinsic to individuals such as infections or diseases with metabolic (diabetes), genetic …

To bring new extrachromosomal circular DNA (eccDNA) enrichment technologies closer to
the clinic, specifically for screening, early diagnosis, and monitoring of diseases or lifestyle …

Osteogenesis imperfecta (OI) describes a series of genetic bone fragility disorders that can
have a substantive impact on patient quality of life. The multidisciplinary approach to …

(1) Background: Osteogenesis imperfecta (OI) is a rare skeletal dysplasia characterized as a
heterogeneous disorder group with well-defined phenotypic and genetic features that share …

With approximately 1.4 million men annually diagnosed with prostate cancer (PCa)
worldwide, PCa remains a dreaded threat to life and source of devastating morbidity. In …

The progressive loss of the regenerative potential of tissues is one of the most obvious
consequences of aging, driven by altered intercellular communication, cell senescence and …