Host–microbiota interactions in inflammatory bowel disease

R Caruso, BC Lo, G Núñez - Nature Reviews Immunology, 2020 - nature.com
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …

An insight into gut microbiota and its functionalities

A Adak, MR Khan - Cellular and Molecular Life Sciences, 2019 - Springer
Gut microbiota has evolved along with their hosts and is an integral part of the human body.
Microbiota acquired at birth develops in parallel as the host develops and maintains its …

Within-host evolution of a gut pathobiont facilitates liver translocation

Y Yang, M Nguyen, V Khetrapal, ND Sonnert, AL Martin… - Nature, 2022 - nature.com
Gut commensal bacteria with the ability to translocate across the intestinal barrier can drive
the development of diverse immune-mediated diseases,,–. However, the key factors that …

Listeria monocytogenes: towards a complete picture of its physiology and pathogenesis

L Radoshevich, P Cossart - Nature Reviews Microbiology, 2018 - nature.com
Listeria monocytogenes is a food-borne pathogen responsible for a disease called
listeriosis, which is potentially lethal in immunocompromised individuals. This bacterium, first …

[HTML][HTML] From bacterial killing to immune modulation: Recent insights into the functions of lysozyme

SA Ragland, AK Criss - PLoS pathogens, 2017 - journals.plos.org
Lysozyme is a cornerstone of innate immunity. The canonical mechanism for bacterial killing
by lysozyme occurs through the hydrolysis of cell wall peptidoglycan (PG). Conventional …

Pathogenicity and virulence of Listeria monocytogenes: A trip from environmental to medical microbiology

JJ Quereda, A Morón-García, C Palacios-Gorba… - Virulence, 2021 - Taylor & Francis
Listeria monocytogenes is a saprophytic gram-positive bacterium, and an opportunistic
foodborne pathogen that can produce listeriosis in humans and animals. It has evolved an …

Pattern recognition receptors and signaling in plant–microbe interactions

Y Saijo, EP Loo, S Yasuda - The Plant Journal, 2018 - Wiley Online Library
Plants solely rely on innate immunity of each individual cell to deal with a diversity of
microbes in the environment. Extracellular recognition of microbe‐and host damage …

Peptidoglycan recognition by the innate immune system

AJ Wolf, DM Underhill - Nature Reviews Immunology, 2018 - nature.com
The innate immune system recognizes microbial products using germline-encoded
receptors that initiate inflammatory responses to infection. The bacterial cell wall component …

[HTML][HTML] How bacterial pathogens colonize their hosts and invade deeper tissues

D Ribet, P Cossart - Microbes and infection, 2015 - Elsevier
Bacterial pathogens have evolved a wide range of strategies to colonize and invade human
organs, despite the presence of multiple host defense mechanisms. In this review, we will …

[PDF][PDF] NOD1 and NOD2: signaling, host defense, and inflammatory disease

R Caruso, N Warner, N Inohara, G Núñez - Immunity, 2014 - cell.com
The nucleotide-binding oligomerization domain (NOD) proteins NOD1 and NOD2, the
founding members of the intracellular NOD-like receptor family, sense conserved motifs in …