Extreme heterogeneity of human mitochondrial DNA from organelles to populations
JB Stewart, PF Chinnery - Nature Reviews Genetics, 2021 - nature.com
Contrary to the long-held view that most humans harbour only identical mitochondrial
genomes, deep resequencing has uncovered unanticipated extreme genetic variation within …
genomes, deep resequencing has uncovered unanticipated extreme genetic variation within …
Mitochondrial DNA in innate immune responses and inflammatory pathology
Mitochondrial DNA (mtDNA)—which is well known for its role in oxidative phosphorylation
and maternally inherited mitochondrial diseases—is increasingly recognized as an agonist …
and maternally inherited mitochondrial diseases—is increasingly recognized as an agonist …
Is mitochondrial DNA content a potential biomarker of mitochondrial dysfunction?
AN Malik, A Czajka - Mitochondrion, 2013 - Elsevier
Mitochondrial dysfunction is central to numerous diseases of oxidative stress. Changes in
mitochondrial DNA (MtDNA) content, often measured as mitochondrial genome to nuclear …
mitochondrial DNA (MtDNA) content, often measured as mitochondrial genome to nuclear …
Guidelines for DNA taxonomy, with a focus on the meiofauna
Describing biological diversity is a challenging endeavour, especially for the small, cryptic
animals that make up the meiofauna. The field of DNA taxonomy, ie, the use of DNA to …
animals that make up the meiofauna. The field of DNA taxonomy, ie, the use of DNA to …
Mitochondrial diseases: a diagnostic revolution
Mitochondrial disorders have emerged as a common cause of inherited disease, but are
traditionally viewed as being difficult to diagnose clinically, and even more difficult to …
traditionally viewed as being difficult to diagnose clinically, and even more difficult to …
Molecular approaches to trematode systematics:'best practice'and implications for future study
To date, morphological analysis has been the cornerstone to trematode systematics.
However, since the late-1980s we have seen an increased integration of genetic data to …
However, since the late-1980s we have seen an increased integration of genetic data to …
Emerging role of mitochondrial DNA as a major driver of inflammation and disease progression
Inflammation benefits the host by promoting the elimination of invading pathogens and
clearance of cellular debris after tissue injury. Inflammation also stimulates tissue repair and …
clearance of cellular debris after tissue injury. Inflammation also stimulates tissue repair and …
[HTML][HTML] The future of NGS (Next Generation Sequencing) analysis in testing food authenticity
The authenticity of foodstuffs is an important issue for consumers, regulators, producers and
processors, as fraudulent practices can negatively affect consumer confidence and safety …
processors, as fraudulent practices can negatively affect consumer confidence and safety …
Molecular tools and analytical approaches for the characterization of farm animal genetic diversity
JA Lenstra, LF Groeneveld, H Eding… - Animal …, 2012 - Wiley Online Library
Genetic studies of livestock populations focus on questions of domestication, withinand
amongbreed diversity, breed history and adaptive variation. In this review, we describe the …
amongbreed diversity, breed history and adaptive variation. In this review, we describe the …
[PDF][PDF] A revolutionary protocol to describe understudied hyperdiverse taxa and overcome the taxonomic impediment
S Meierotto, MJ Sharkey, DH Janzen… - Deutsche …, 2019 - dez.pensoft.net
Here we elucidate and justify a DNA barcode approach to insect species description that
can be applied to name tens of thousands of species of Ichneumonoidea and many other …
can be applied to name tens of thousands of species of Ichneumonoidea and many other …