Pathophysiology of adult obstructive sleep apnea

DJ Eckert, A Malhotra - Proceedings of the American thoracic …, 2008 - atsjournals.org
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive narrowing
or collapse of the pharyngeal airway during sleep. The disorder is associated with major …

Role of respiratory control mechanisms in the pathogenesis of obstructive sleep disorders

M Younes - Journal of applied physiology, 2008 - journals.physiology.org
Obstructive sleep disorders develop when the normal reduction in pharyngeal dilator activity
at sleep onset occurs in an individual whose pharynx requires a relatively high level of …

Work of breathing and respiratory drive in obesity

CK Lin, CC Lin - Respirology, 2012 - Wiley Online Library
Obesity, particularly severe central obesity, affects respiratory physiology both at rest and
during exercise. Reductions in expiratory reserve volume, functional residual capacity …

Obesity and upper airway control during sleep

AR Schwartz, SP Patil, S Squier… - Journal of Applied …, 2010 - journals.physiology.org
Mechanisms linking obesity with upper airway dysfunction in obstructive sleep apnea are
reviewed. Obstructive sleep apnea is due to alterations in upper airway anatomy and …

Obstructive sleep apnea

DP White, MK Younes - Comprehensive Physiology, 2012 - Wiley Online Library
Obstructive sleep apnea (OSA) is a common disorder characterized by repetitive collapse of
the pharyngeal airway during sleep. Control of pharyngeal patency is a complex process …

Upper airway neuromuscular compensation during sleep is defective in obstructive sleep apnea

BM McGinley, AR Schwartz… - Journal of applied …, 2008 - journals.physiology.org
Obstructive sleep apnea is the result of repeated episodes of upper airway obstruction
during sleep. Recent evidence indicates that alterations in upper airway anatomy and …

Determinants of ventilatory instability in obstructive sleep apnea: inherent or acquired?

A Loewen, M Ostrowski, J Laprairie, R Atkar, J Gnitecki… - Sleep, 2009 - academic.oup.com
Abstract Study Objectives: Certain respiratory control characteristics determine whether
patients with collapsible upper airway develop stable or unstable breathing during sleep …

Sensorimotor function of the upper-airway muscles and respiratory sensory processing in untreated obstructive sleep apnea

DJ Eckert, YL Lo, JP Saboisky… - Journal of applied …, 2011 - journals.physiology.org
Numerous studies have demonstrated upper-airway neuromuscular abnormalities during
wakefulness in snorers and obstructive sleep apnea (OSA) patients. However, the functional …

[HTML][HTML] Is laryngeal hypersensitivity the basis of unexplained or refractory chronic cough?

KM Sundar, AC Stark, N Hu… - ERJ Open …, 2021 - Eur Respiratory Soc
Refractory chronic cough (RCC) and unexplained chronic cough (UCC) are common
problems seen in primary care and subspecialty clinics. The role of cough hypersensitivity …

[HTML][HTML] Neural control of the upper airway: respiratory and state-dependent mechanisms

L Kubin - Comprehensive Physiology, 2016 - ncbi.nlm.nih.gov
Upper airway muscles subserve many essential for survival orofacial behaviors, including
their important role as accessory respiratory muscles. In the face of certain predisposition of …