Alzheimer's disease: past, present, and future

MW Bondi, EC Edmonds, DP Salmon - Journal of the International …, 2017 - cambridge.org
Although dementia has been described in ancient texts over many centuries (eg,“Be kind to
your father, even if his mind fail him.”–Old Testament: Sirach 3: 12), our knowledge of its …

Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2017 - Elsevier
Abstract Introduction The Alzheimer's Disease Neuroimaging Initiative (ADNI) has continued
development and standardization of methodologies for biomarkers and has provided an …

[HTML][HTML] Genetic studies of quantitative MCI and AD phenotypes in ADNI: Progress, opportunities, and plans

AJ Saykin, L Shen, X Yao, S Kim, K Nho… - Alzheimer's & …, 2015 - Elsevier
Introduction Genetic data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) have
been crucial in advancing the understanding of Alzheimer's disease (AD) pathophysiology …

Robust hybrid deep learning models for Alzheimer's progression detection

T Abuhmed, S El-Sappagh, JM Alonso - Knowledge-Based Systems, 2021 - Elsevier
The prevalence of Alzheimer's disease (AD) in the growing elderly population makes
accurately predicting AD progression crucial. Due to AD's complex etiology and …

Predicting progression from mild cognitive impairment to Alzheimer's dementia using clinical, MRI, and plasma biomarkers via probabilistic pattern classification

IO Korolev, LL Symonds, AC Bozoki… - PloS one, 2016 - journals.plos.org
Background Individuals with mild cognitive impairment (MCI) have a substantially increased
risk of developing dementia due to Alzheimer's disease (AD). In this study, we developed a …

Rey's Auditory Verbal Learning Test scores can be predicted from whole brain MRI in Alzheimer's disease

E Moradi, I Hallikainen, T Hänninen, J Tohka… - NeuroImage: Clinical, 2017 - Elsevier
Abstract Rey's Auditory Verbal Learning Test (RAVLT) is a powerful neuropsychological tool
for testing episodic memory, which is widely used for the cognitive assessment in dementia …

Diagnostic accuracy of memory measures in Alzheimer's dementia and mild cognitive impairment: A systematic review and meta-analysis

GH Weissberger, JV Strong, KB Stefanidis… - Neuropsychology …, 2017 - Springer
With an increasing focus on biomarkers in dementia research, illustrating the role of
neuropsychological assessment in detecting mild cognitive impairment (MCI) and …

The vascular hypothesis of Alzheimer's disease: a key to preclinical prediction of dementia using neuroimaging

J De La Torre - Journal of Alzheimer's Disease, 2018 - content.iospress.com
The vascular hypothesis of Alzheimer's disease (VHAD) was proposed 24 years ago from
observations made in our laboratory using aging rats subjected to chronic brain …

Does mild cognitive impairment always lead to dementia? A review

SY Pandya, MA Clem, LM Silva, FL Woon - Journal of the neurological …, 2016 - Elsevier
Mild cognitive impairment (MCI) has often been studied in its association with dementia, yet
higher rates of reversion to normal cognition than progression to dementia suggest that MCI …

[HTML][HTML] FDG-PET and CSF biomarker accuracy in prediction of conversion to different dementias in a large multicentre MCI cohort

SP Caminiti, T Ballarini, A Sala, C Cerami, L Presotto… - NeuroImage: Clinical, 2018 - Elsevier
Background/aims In this multicentre study in clinical settings, we assessed the accuracy of
optimized procedures for FDG-PET brain metabolism and CSF classifications in predicting …