Medicinal and therapeutic potential of herbs and plant metabolites/extracts countering viral pathogens-current knowledge and future prospects
Background: Recently, there has been a remarkable progress in the field of antiviral herbal
therapy owing to increasing concerns about the development of drug resistance and limited …
therapy owing to increasing concerns about the development of drug resistance and limited …
[HTML][HTML] The impact of HIV-and ART-induced mitochondrial dysfunction in cellular senescence and aging
M Schank, J Zhao, JP Moorman, ZQ Yao - Cells, 2021 - mdpi.com
According to the WHO, 38 million individuals were living with human immunodeficiency virus
(HIV), 25.4 million of which were using antiretroviral therapy (ART) at the end of 2019 …
(HIV), 25.4 million of which were using antiretroviral therapy (ART) at the end of 2019 …
[HTML][HTML] Myristoylation: an important protein modification in the immune response
Protein N-myristoylation is a cotranslational lipidic modification specific to the alpha-amino
group of an N-terminal glycine residue of many eukaryotic and viral proteins. The ubiquitous …
group of an N-terminal glycine residue of many eukaryotic and viral proteins. The ubiquitous …
Basics of the virology of HIV-1 and its replication
S Sierra, B Kupfer, R Kaiser - Journal of clinical virology, 2005 - Elsevier
Human immunodeficiency virus is undoubtedly the causative agent of AIDS. The
understanding of HIV-1 pathogenesis is essentiell to develop and maintain antiretroviral …
understanding of HIV-1 pathogenesis is essentiell to develop and maintain antiretroviral …
[HTML][HTML] Bryostatin modulates latent HIV-1 infection via PKC and AMPK signaling but inhibits acute infection in a receptor independent manner
R Mehla, S Bivalkar-Mehla, R Zhang, I Handy… - PloS one, 2010 - journals.plos.org
HIV's ability to establish long-lived latent infection is mainly due to transcriptional silencing in
resting memory T lymphocytes and other non dividing cells including monocytes. Despite an …
resting memory T lymphocytes and other non dividing cells including monocytes. Despite an …
Multifunctional role of exosomes in viral diseases: From transmission to diagnosis and therapy
P Chaudhari, V Ghate, M Nampoothiri, S Lewis - Cellular signalling, 2022 - Elsevier
Efforts to discover antiviral drugs and diagnostic platforms have intensified to an
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …
unprecedented level since the outbreak of COVID-19. Nano-sized endosomal vesicles …
[HTML][HTML] Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse
MI Thoulouze, N Sol-Foulon, F Blanchet… - Immunity, 2006 - cell.com
HIV-1-infected lymphocytes improperly respond to T cell antigen receptor (TCR) stimulation.
To document this phenomenon, we studied the capacity of HIV-1-infected lymphocytes to …
To document this phenomenon, we studied the capacity of HIV-1-infected lymphocytes to …
[HTML][HTML] Ginseng, the natural effectual antiviral: Protective effects of Korean Red Ginseng against viral infection
K Im, J Kim, H Min - Journal of ginseng research, 2016 - Elsevier
Abstract Korean Red Ginseng (KRG) is a heat-processed ginseng developed by the
repeated steaming and air-drying of fresh ginseng. Compared with fresh ginseng, KRG has …
repeated steaming and air-drying of fresh ginseng. Compared with fresh ginseng, KRG has …
TNF and TNF receptor superfamily members in HIV infection: new cellular targets for therapy?
Tumor necrosis factor (TNF) and TNF receptors (TNFR) superfamily members are engaged
in diverse cellular phenomena such as cellular proliferation, morphogenesis, apoptosis …
in diverse cellular phenomena such as cellular proliferation, morphogenesis, apoptosis …
The HIV Nef protein modulates cellular and exosomal miRNA profiles in human monocytic cells
Introduction The HIV Nef protein is a multifunctional virulence factor that perturbs
intracellular membranes and signalling and is secreted into exosomes. While Nef-containing …
intracellular membranes and signalling and is secreted into exosomes. While Nef-containing …