Cytochrome c, a protein that belongs to class 1 of the c-type cytochrome family, exerts
different functions depending on its cellular localization and the conditions in which it …

Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

Barth syndrome (BTHS) is a life-threatening genetic disorder with unknown pathogenicity
caused by mutations in TAFAZZIN (TAZ) that affect remodeling of mitochondrial cardiolipin …

Cytochrome c, released from mitochondria into the cytosol, triggers formation of the
apoptosome resulting in activation of caspases. This paper reviews the evidence for and …

The regular functioning of the nucleolus and nucleus-mitochondria crosstalk are considered
unrelated processes, yet cytochrome c (C c) migrates to the nucleus and even the nucleolus …

We report the first identified mutation in the gene encoding human cytochrome c (CYCS).
Glycine 41, invariant throughout eukaryotes, is substituted by serine in a family with …

At the onset of apoptosis, the peroxidation of cardiolipin at the inner mitochondrial
membrane by cytochrome c requires an open coordination site on the heme. We report a …

Cytochrome c is a well-known mitochondrial protein that fulfills life-supporting functions by
transferring electrons to the respiratory chain to maintain ATP production. However, during …

Since the first description of apoptosis four decades ago, great efforts have been made to
elucidate, both in vivo and in vitro, the molecular mechanisms involved in its regulation …

Recently, electron transfers and catalyses in a bevy of redox reactions mediated by
hemeproteins were explained by murburn concept. The term “murburn” is abstracted from …