Technology trends in antibody purification

P Gagnon - Journal of chromatography A, 2012 - Elsevier
This article reviews technology trends in antibody purification. Section 1 discusses non-
chromatography methods, including precipitation, liquid–liquid extraction, and high …

Protein A chromatography: Challenges and progress in the purification of monoclonal antibodies

AM Ramos‐de‐la‐Peña… - Journal of separation …, 2019 - Wiley Online Library
Antibodies for therapeutic use are being continuously approved and their demand has been
steadily growing. As known, the golden standard for monoclonal antibody (mAb) purification …

[图书][B] Handbook of membrane separations: chemical, pharmaceutical, food, and biotechnological applications

AK Pabby, SSH Rizvi, AMS Requena - 2008 - taylorfrancis.com
The Handbook of Membrane Separations: Chemical, Pharmaceutical, and Biotechnological
Applications provides detailed information on membrane separation technologies as they …

A direct comparison between membrane adsorber and packed column chromatography performance

C Boi, A Malavasi, RG Carbonell, G Gilleskie - Journal of Chromatography …, 2020 - Elsevier
The purpose of this work was to compare side by side the performance of packed bed and
membrane chromatography adsorption processes for protein purification. The comparison …

Antibody purification with protein A attached supermacroporous poly (hydroxyethyl methacrylate) cryogel

H Alkan, N Bereli, Z Baysal, A Denizli - Biochemical engineering journal, 2009 - Elsevier
Immunoglobulin G (IgG) purification from human plasma with protein A attached
supermacroporous poly (hydroxyethyl methacrylate)[PHEMA] cryogel has been studied …

Intensified downstream processing of monoclonal antibodies using membrane technology

S Nadar, G Shooter, B Somasundaram… - Biotechnology …, 2021 - Wiley Online Library
The need to intensify downstream processing of monoclonal antibodies to complement the
advances in upstream productivity has led to increased attention toward implementing …

Affinity membranes and monoliths for protein purification

E Lalli, JS Silva, C Boi, GC Sarti - Membranes, 2019 - mdpi.com
Affinity capture represents an important step in downstream processing of proteins and it is
conventionally performed through a chromatographic process. The performance of this step …

Comparative evaluation of commercial protein A membranes for the rapid purification of antibodies

J Osuofa, SM Husson - Membranes, 2023 - mdpi.com
Protein A chromatography is ubiquitous to antibody purification. The high specificity of
Protein A for binding the Fc-region of antibodies and related products enables unmatched …

Technology advancements in antibody purification

C Murphy, T Devine, R O'Kennedy - Antibody Technology Journal, 2016 - Taylor & Francis
The separation of antibodies from complex mixtures can be achieved using
chromatographic or non-chromatographic techniques. The purification of antibodies using …

Polypropylene nonwoven fabrics with conformal grafting of poly (glycidyl methacrylate) for bioseparations

Y Zheng, H Liu, PV Gurgel, RG Carbonell - Journal of membrane science, 2010 - Elsevier
Nonwovens fabrics are porous materials with great potential for use in the separation and
purification of biotherapeutic proteins and other biomolecules after proper surface activation …