Drug-induced liver injury is a potential complication of nearly every medication that is
prescribed, because the liver is central to the metabolic disposition of virtually all drugs and …

Antibiotics used by general practitioners frequently appear in adverse-event reports of drug-
induced hepatotoxicity. Most cases are idiosyncratic (the adverse reaction cannot be …

The validity of drug exposure measurement based on pharmacy records was investigated
taking into account completeness of data, drug compliance, and different methods of drug …

Featuring more than 4100 references, Drug-Induced Liver Disease is an invaluable
reference for gastroenterologists, hepatologists, family physicians, internists, pathologists …

Of the numerous medicinal agents, chemicals, and herbal remedies in existence, more than
600 are recognized as producing hepatic injury. 2o5 The incidence of drug-induced liver …

Background: Because minocycline can cause serious adverse events including
hypersensitivity syndrome reaction (HSR), serum sicknesslike reaction (SSLR), and …

Background: Amoxicillin—clavulanic acid combination—associated hepatitis and jaundice
was first identified in 1988. Numerous case reports and case series have been published …

Background Methodological research to evaluate the performance of methods requires a
benchmark to serve as a referent comparison. In drug safety, the performance of analyses of …

Drug-induced acute liver failure (ALF) accounts for approximately 20% of ALF in children
and a higher percentage of ALF in adults. Although most patients experience milder drug …

The article discusses the efficacy of drug-induced liver injury. It is considered the most
common causes for termination of drug development which classified as cholestatic …