Small-cell lung cancer

CM Rudin, E Brambilla, C Faivre-Finn… - Nature Reviews Disease …, 2021 - nature.com
Small-cell lung cancer (SCLC) represents about 15% of all lung cancers and is marked by
an exceptionally high proliferative rate, strong predilection for early metastasis and poor …

Recent developments in the treatment of small cell lung cancer

BI Hiddinga, J Raskin, A Janssens… - European …, 2021 - Eur Respiratory Soc
Small cell lung cancer (SCLC) comprises about 15% of all lung cancers. It is an aggressive
disease, with early metastasis and a poor prognosis. Until recently, SCLC treatment …

Expression patterns and prognostic relevance of subtype‐specific transcription factors in surgically resected small‐cell lung cancer: an international multicenter study

Z Megyesfalvi, N Barany, A Lantos… - The Journal of …, 2022 - Wiley Online Library
The tissue distribution and prognostic relevance of subtype‐specific proteins (ASCL1,
NEUROD1, POU2F3, YAP1) present an evolving area of research in small‐cell lung cancer …

[HTML][HTML] Small-cell lung cancer brain metastasis: from molecular mechanisms to diagnosis and treatment

Y Zhu, Y Cui, X Zheng, Y Zhao, G Sun - Biochimica et Biophysica Acta (BBA …, 2022 - Elsevier
Lung cancer is the most malignant human cancer worldwide, also with the highest incidence
rate. However, small-cell lung cancer (SCLC) accounts for 14% of all lung cancer cases …

Histone modification in NSCLC: molecular mechanisms and therapeutic targets

K Bajbouj, A Al-Ali, RK Ramakrishnan… - International journal of …, 2021 - mdpi.com
Lung cancer is the leading cause of cancer mortality in both genders, with non-small cell
lung cancer (NSCLC) accounting for about 85% of all lung cancers. At the time of diagnosis …

Patient burden and real-world management of chemotherapy-induced myelosuppression: results from an online survey of patients with solid tumors

RS Epstein, MS Aapro, UK Basu Roy, T Salimi… - Advances in …, 2020 - Springer
Introduction Chemotherapy-induced myelosuppression (CIM) is one of the most common
dose-limiting complications of cancer treatment, and is associated with a range of …

Morphologic and molecular classification of lung neuroendocrine neoplasms

J Metovic, M Barella, F Bianchi, P Hofman, V Hofman… - Virchows Archiv, 2021 - Springer
Neuroendocrine neoplasms (NENs) of the lung encompass neuroendocrine tumors (NETs)
composed of typical (TC) and atypical (AC) carcinoids and full-fledged carcinomas (NECs) …

Emerging biomarkers and the changing landscape of small cell lung cancer

A Keogh, S Finn, T Radonic - Cancers, 2022 - mdpi.com
Simple Summary Small cell lung cancer (SCLC) is an aggressive cancer representing 15%
of all lung cancers. Unlike other types of lung cancer, treatments for SCLC have changed …

A comprehensive and current review on the role of flavonoids in lung cancer–Experimental and theoretical approaches

Ş Berk, S Kaya, EK Akkol, H Bardakçı - Phytomedicine, 2022 - Elsevier
Background It is well-known that flavonoids, which can be easily obtained from many fruits
and vegetables are widely preferred in the treatment of some important diseases. Some …

Current status of immune checkpoint inhibitor immunotherapy for lung cancer

W Xiong, Y Zhao, H Du, X Guo - Frontiers in oncology, 2021 - frontiersin.org
Immunotherapy is a major breakthrough in the treatment of cancer in recent years. Immune
checkpoint inhibitors (ICIs) including programmed death-ligand 1 (PD-L1)/programmed …