The relevance of vitamin D receptor (VDR) gene polymorphisms for cancer: a review of the literature

KIM Köstner, N Denzer, CSL Mueller, R Klein… - Anticancer …, 2009 - ar.iiarjournals.org
Background: In recent years, the relevance of vitamin D receptor (VDR) gene restriction
fragment length polymorphisms for various types of cancer has been investigated by a great …

Vitamin D gene pathway polymorphisms and risk of colorectal, breast, and prostate cancer

ML McCullough, RM Bostick… - Annual review of nutrition, 2009 - annualreviews.org
Higher vitamin D exposure is hypothesized to prevent several cancers, possibly through
genomic effects modulated by the vitamin D receptor (VDR), and autocrine/paracrine …

Vitamin D receptor polymorphisms and cancer

P Gnagnarella, S Raimondi, V Aristarco… - Sunlight, Vitamin D and …, 2020 - Springer
Increasing scientific evidence supports the link between vitamin D and cancer risk. The
active metabolite 1, 25 (OH) 2D exerts its activity by binding to the vitamin D receptor (VDR) …

Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy

JM Pendleton, WW Tan, S Anai, M Chang, W Hou… - BMC cancer, 2008 - Springer
Background-Data exist that demonstrate isoflavones' potent antiproliferative effects on
prostate cancer cells. We evaluated the efficacy of isoflavone in patients with PSA recurrent …

Coordination between polymerase β and FEN1 can modulate CAG repeat expansion

Y Liu, R Prasad, WA Beard, EW Hou, JK Horton… - Journal of Biological …, 2009 - ASBMB
The oxidized DNA base 8-oxoguanine (8-oxoG) is implicated in neuronal CAG repeat
expansion associated with Huntington disease, yet it is unclear how such a DNA base lesion …

Meta-analysis on vitamin D receptor and cancer risk: focus on the role of TaqI, ApaI, and Cdx2 polymorphisms

D Serrano, P Gnagnarella, S Raimondi… - European Journal of …, 2016 - journals.lww.com
Vitamin D plays a significant role in our health, including cancer incidence and mortality.
Vitamin D receptor (VDR) single-nucleotide polymorphisms (SNPs) may affect its activity …

[图书][B] Bioactive foods and extracts: Cancer treatment and prevention

RR Watson, VR Preedy - 2010 - books.google.com
A review of the recent surge in research related to the effect of plant products in cancer
treatment, Bioactive Foods and Extracts: Cancer Treatment and Prevention organizes cutting …

Androgen receptor gene polymorphisms and risk of prostate cancer: a meta-analysis

H Weng, S Li, JY Huang, ZQ He, XY Meng, Y Cao… - Scientific reports, 2017 - nature.com
Although the association between CAG and GGN repeats in the androgen receptor gene
and prostate cancer risk has been widely studied, it remains controversial from previous …

[HTML][HTML] Vitamin D receptor gene (VDR) associations with cancer

ML Slattery - Nutrition reviews, 2007 - ncbi.nlm.nih.gov
In 1969 the nuclear vitamin D receptor (VDR) for 1α25 (OH) 2D3 was discovered. 1 Since
then, the role of VDR in the endocrine system and its presence and function in over 30 …

[HTML][HTML] Significant association of Poly-A and Fok1 polymorphic alleles of the vitamin D receptor with vitamin D serum levels and incidence of squamous cutaneous …

TA Bullock, JA Mack, J Negrey, U Kaw, B Hu… - Journal of Investigative …, 2023 - Elsevier
Vitamin D3, a prohormone, is converted to circulating calcidiol and then to calcitriol, the
hormone that binds to the vitamin D receptor (VDR)(a nuclear transcription factor) …